Nick Barker

Research Director

Institute of Molecular and Cell Biology

Nick Barker is currently a Research Director at A*STAR’s Institute of Molecular and Cell Biology (IMCB) and a Visiting Professor at Kanazawa University, Japan. Barker obtained his PhD from Reading University, UK in 1996. Together with Professor Hans Clevers, he identified dysregulated Wnt signaling as the initiating event in colon cancer. In 2001, he joined Semaia Pharmaceuticals to develop colon cancer therapeutics, then returned to Hans Clevers’ group as a Senior Staff Scientist in 2006, where he identified Lgr5 as a marker of various adult stem cell populations and intestinal Lgr5 stem cells as a cell-of-origin of colon cancer. In 2017, he received the prestigious NRF Investigatorship and is recognized as a Web of Science Highly Cited Researcher.

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