Nick Barker is Deputy Executive Director at the A*STAR Institute of Molecular and Cell Biology (A*STAR IMCB). He is also an Adjunct Professor at the National University of Singapore (NUS) Yong Loo Lin School of Medicine, Singapore, and an Honorary Professor at University of Newcastle, Australia. Barker obtained his PhD degree from Reading University, UK, in 1996. Together with Professor Hans Clevers, he identified dysregulated Wnt signalling as the initiating event in colon cancer. Moving to Singapore in 2010, he joined A*STAR’s Institute of Medical Biology (IMB) as a Senior Principal Investigator before moving to his current position at A*STAR IMCB.
Barker’s research focuses on LGR5+ and AQP5+ stem cells in tissue homeostasis and cancer within the gastrointestinal tract. In 2017, he received the prestigious NRF Investigatorship and has been recognised as a Web of Science Highly Cited Researcher since 2019 with over 42,000 citations. In 2022, he was elected to EMBO as an Associate Member and was awarded the Japanese Cancer Association International prize for cancer research.
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