Bioinformatics Institute (BII)

Researchers develop a protocol to boost the effectiveness of and reduce the risk of potential side effects for T cell cancer therapies.

By exploring the genetic diversity within Escherichia coli bacteria, researchers uncover distinct gene families and a molecular weapon tied to disease-causing strains.

Researchers identify an unexpected synergy between bacterial and viral molecules that causes severe inflammation in some patients with COVID-19.

Inactivated COVID-19 vaccines could be an equally potent alternative for people with allergic sensitivities to mRNA-based vaccines.

Researchers develop machine learning models for accurately diagnosing an inflammatory skin condition.

Despite the hype, State-of-the-art machine learning challenges one of the toughest problems in systems biology.

Molecular simulations uncover a new druggable pocket in SARS-CoV-2’s spike protein which could hold the key to blocking COVID-19 infections.

A new polymer gel may offer a drug-free solution to preventing retinal scarring after eye surgery.

Multidisciplinary efforts across A*STAR are paving the way toward Singapore’s precision medicine vision.

A user-friendly online computational platform helps researchers scour complex datasets to predict how likely food proteins are to trigger allergic reactions.

A*STAR scientists lay the foundations for a circular economy using worms that turn plastics into fertiliser.

A computational model developed at A*STAR provides insights on how molecular dynamics of proteins impact their function, unlocking new precision medicine opportunities.