A*STAR Bioinformatics Institute (A*STAR BII)
A twist in the tale of stapled peptides
15 May 2025A new molecular dynamics study reveals how some stapled peptides shapeshift to slip through cellular barriers and target key disease-related proteins within cells.
Smart solutions for custom cancer care
27 Mar 2025A new machine learning tool could help predict cancer treatment outcomes for more effective and targeted treatments.
Tuning in to cellular conversations
8 Jan 2025A new artificial intelligence tool helps scientists uncover how cells communicate within tissues, paving the way for more targeted treatments for diseases like cancer.
Guiding stars at scientific frontiers
6 Jan 2025In recognition of their scientific contributions and impact both locally and globally, 14 leading researchers have been awarded the 2024 A*STAR Fellowship.
Gene trails lead to a new view of diabetes
26 Dec 2024A comprehensive genomic map reveals how certain genes regulate key cells in blood sugar control, offering new insights for future diabetes treatments.
Exploring cells’ community ties
20 Dec 2024A new algorithm, BANKSY, expands our understanding of cellular diversity by revealing how cells are influenced by interactions with their neighbours.
Evolving enzymes for greener goods
12 Dec 2024A*STAR researchers develop new tools to speed up the development of potent enzymes for oxidising complex alcohol molecules, providing more options for a challenging synthesis step in sustainable chemical manufacturing.
Taming T cells to douse eczema’s flare
22 Nov 2024A*STAR researchers discovered a potential new treatment for severe eczema by targeting a protein that regulates immune cell activity.
Reinforcing frontline defences against variants
14 Nov 2024Antibodies in mucous membranes may be key in protecting against SARS-CoV-2 variants, pointing to the need for COVID-19 vaccines that target these antibody responses.
Steadying antibodies against variant surges
23 Oct 2024A high-resolution study of SARS-CoV-2 antibodies revealed how they neutralise variants and reduce the impact of spike protein mutations.
Digital detective decodes dementia
3 Oct 2024A new machine learning model identifies key dementia features from complex clinical datasets, potentially making diagnoses faster and less subjective.
Shaping solutions to fix faulty cells
25 Sep 2024Innovative designer molecules called stapled peptides effectively target and block cancer processes, promising a new therapeutic approach.