Bioinformatics Institute (BII)
A*STAR scientists aim to design better immunotherapies by simulating the binding of antibodies to their targets.
A*STAR scientists have identified drug compounds that could potentially eradicate an aggressive form of liver cancer by targeting a metabolic vulnerability induced by the SALL4 oncogene.
A better understanding of the way sugar units are attached to the surface proteins of cancer cells may help to improve targeted cancer treatments, A*STAR scientists say.
A*STAR researchers have identified specific sites in the surface protein of influenza viruses that allow the pathogen to adapt to different host organisms.
Researchers at A*STAR have combined two superresolution microscopy techniques to observe structural protein dynamics inside cells.
Short- and long-range interactions that give structure to virus genomes also influence virus replication and infectiousness.
Need to monitor how well a wound is healing? There’s an app for that.
An automated machine learning system for analyzing leg movements in fruit flies is helping A*STAR researchers shed light on how neurodegenerative diseases develop.
The host immune system has a limited impact on the evolution of the influenza virus, A*STAR researchers find.
The AllerCatPro analysis workflow helps researchers predict the likelihood of a protein producing an allergic response in people.
The rate of discovery of human gene functions has fallen significantly