Bioinformatics Institute (BII)
A genetic discovery reveals why some aggressive carcinomas do not respond to standard treatment and suggest a more effective option.
Exploiting a mutation in a key tumor-fighting protein may provide a new opportunity to treat aggressive lung cancers.
Antibodies that recognize the SARS-CoV-2 spike protein show potential for diagnosing COVID-19.
Sebastian Maurer-Stroh shares how bioinformatics has enabled Singapore to respond quickly to COVID-19 and will continue to play an important role in ongoing surveillance.
Studying how viruses change their shapes at different temperatures could lead to more effective vaccines.
Surveillance and contact tracing are key to limiting the widespread transmission of COVID-19 in the community, experts find.
Scientists at A*STAR have found that a mutation in SARS-CoV-2 called ∆382 leads to milder clinical outcomes, with implications for COVID-19 treatments and vaccines.
Two early cases of COVID-19 in Thailand represent the first confirmed exported cases from China, a Thai-Singapore team reports.
In a display of scientific willpower, A*STAR researchers developed and deployed the COVID-19 diagnostic Fortitude Kit within weeks of the virus reaching Singapore’s shores.
A*STAR scientists aim to design better immunotherapies by simulating the binding of antibodies to their targets.
A*STAR scientists have identified drug compounds that could potentially eradicate an aggressive form of liver cancer by targeting a metabolic vulnerability induced by the SALL4 oncogene.
A better understanding of the way sugar units are attached to the surface proteins of cancer cells may help to improve targeted cancer treatments, A*STAR scientists say.