Placing cancer under lockdown31 Mar 2021
New insights into the tumor microenvironment may help researchers stop the growth and spread of cancer to other parts of the body.
Targeting triple-negative breast cancer10 Mar 2020
A*STAR scientists have identified a microRNA that can potentially be targeted for the treatment of triple-negative breast cancer.
Detecting illegal assemblies in cancer cells31 Dec 2019
A*STAR scientists have developed a method to measure crucial protein-protein interactions in cancer cells, with implications for drug design and discovery.
Protein-protein interactions made visible20 Dec 2019
A*STAR researchers have turned a bacterial protein into a biosensor that can be used to visualize interactions between proteins.
Sweet serendipity unveils anticancer strategy29 Nov 2019
A better understanding of the way sugar units are attached to the surface proteins of cancer cells may help to improve targeted cancer treatments, A*STAR scientists say.
A stabilizing strategy to keep cancer cells in check29 Nov 2019
Bortezomib, a drug that inhibits the ‘waste disposal system’ in animal cells, could be used to suppress cell division in cancer.
How promoters predict patient outcomes7 Nov 2019
A*STAR researchers demonstrate how the expression of genes from alternative gene promoters is associated with lower cancer survival in patients.
Out for blood in the fight against cancer30 Sep 2019
By interfering with the production and downstream activity of a molecule called Agrin in tumors, scientists can stop the sprouting of blood vessels that promote cancer progression.
Targeting cancer from the inside out13 Aug 2019
In times of stress, cancer cells move a protein normally found inside the cell to the cell surface, making it accessible to antibodies for immunotherapy.
Sniffing out high-risk EBV strains29 Jul 2019
A*STAR scientists have identified two Epstein-Barr virus strains associated with a high risk of causing nasopharyngeal carcinoma.
Starving liver cancer cells into submission29 Jul 2019
Researchers reveal that the buildup of branched-chain amino acids fuels the growth and aggressiveness of liver cancer cells.
Chipping away at drug resistance30 Apr 2019
A platform for rapidly profiling mutations and gene expression offers valuable insights into cancer biology