A*STAR scientists have developed a method to measure crucial protein-protein interactions in cancer cells, with implications for drug design and discovery.
A*STAR researchers have turned a bacterial protein into a biosensor that can be used to visualize interactions between proteins.
A better understanding of the way sugar units are attached to the surface proteins of cancer cells may help to improve targeted cancer treatments, A*STAR scientists say.
Bortezomib, a drug that inhibits the ‘waste disposal system’ in animal cells, could treat cancer by indirectly stabilizing a protein that suppresses cell division.
A*STAR researchers demonstrate how the expression of genes from alternative gene promoters is associated with lower cancer survival in patients.
By interfering with the production and downstream activity of a molecule called Agrin in tumors, scientists can stop the sprouting of blood vessels that promote cancer progression.
In times of stress, cancer cells move a protein normally found inside the cell to the cell surface, making it accessible to antibodies for immunotherapy.
A*STAR scientists have identified two Epstein-Barr virus strains associated with a high risk of causing nasopharyngeal carcinoma.
Researchers reveal that the buildup of branched-chain amino acids fuels the growth and aggressiveness of liver cancer cells.
A platform for rapidly profiling mutations and gene expression offers valuable insights into cancer biology
Mapping the replacement of dead cells in the intestine uncovers a critical stem cell pool