Cancer biology

New insights into the tumor microenvironment may help researchers stop the growth and spread of cancer to other parts of the body.

A*STAR scientists have identified a microRNA that can potentially be targeted for the treatment of triple-negative breast cancer.

A*STAR scientists have developed a method to measure crucial protein-protein interactions in cancer cells, with implications for drug design and discovery.

A*STAR researchers have turned a bacterial protein into a biosensor that can be used to visualize interactions between proteins.

A better understanding of the way sugar units are attached to the surface proteins of cancer cells may help to improve targeted cancer treatments, A*STAR scientists say.

Bortezomib, a drug that inhibits the ‘waste disposal system’ in animal cells, could be used to suppress cell division in cancer.

A*STAR researchers demonstrate how the expression of genes from alternative gene promoters is associated with lower cancer survival in patients.

By interfering with the production and downstream activity of a molecule called Agrin in tumors, scientists can stop the sprouting of blood vessels that promote cancer progression.

In times of stress, cancer cells move a protein normally found inside the cell to the cell surface, making it accessible to antibodies for immunotherapy.

A*STAR scientists have identified two Epstein-Barr virus strains associated with a high risk of causing nasopharyngeal carcinoma.

Researchers reveal that the buildup of branched-chain amino acids fuels the growth and aggressiveness of liver cancer cells.

A platform for rapidly profiling mutations and gene expression offers valuable insights into cancer biology