A genetic discovery reveals why some aggressive carcinomas do not respond to standard treatment and suggest a more effective option.
Exploiting a mutation in a key tumor-fighting protein may provide a new opportunity to treat aggressive lung cancers.
A protein known to switch on DNA repair genes also ‘pauses’ the cell cycle in response to DNA damage, A*STAR researchers find.
Researchers have pieced together a series of molecular events that trigger the progression of chronic myeloid leukemia to its acute phase—the ‘blast crisis.’
A study implicates novel genetic risk factors in a rare and aggressive lymphoma affecting Asian populations.
A novel targeting strategy may make pave the way for effective cancer immunotherapy against previously ‘undruggable’ targets.
Cancer cells evade Taxol-induced cell death by downregulating the expression of a protein known as BimEL.
State-of-the-art single-cell RNA sequencing technologies shed light on the mechanisms through which cancer cells become resistant to tumor-treating drugs
Drug screen reveals safe, potent, broad-spectrum anticancer compound
A new imaging method could reduce the number of repeat operations for breast cancer
An antibody that targets a protein on the surface of stem cells also targets the same protein on some cancer cells