Cell biology
A tough choice for embryo cells
25 Jan 2021Keratin, a tough and insoluble fibrous protein, plays a surprising role in determining mouse embryonic cell fate.
Advanced microscopy catches cells going out on a limb
23 Sep 2019Researchers at A*STAR have combined two superresolution microscopy techniques to observe structural protein dynamics inside cells.
How cancer cells tip the Bim balance in their favor
24 May 2019Cancer cells evade Taxol-induced cell death by downregulating the expression of a protein known as BimEL.
Getting mature human heart muscle cells to multiply again
24 May 2019By triggering the Wnt signaling pathway, A*STAR scientists were able to reactivate proliferation in mature human heart muscle cells.
Growing a ‘spine’ on a chip
24 May 2019Microfluidic device allows for precise control of growth factor gradients, mimicking natural spinal cord development in vitro.
Charting T cell territory
18 Apr 2017An
atlas of immune cells shows unexpected complexity, but could ultimately offer
valuable clinical insights
Nurturing neurons
13 Dec 2016A strategy for efficiently converting stem cells to neurons offers a potent neurological research tool
Patterning pluripotency
8 Mar 2016Insights into how external mechanical
forces affect stem cell behavior could advance regenerative medicine efforts
Giving immune cells ‘indigestion’
31 Mar 2015A deadly bacterium uses cellular proteins as bait to sabotage a pathway that enables immune response
Seeking stem cells
17 Feb 2015Fluorescent tagging enables scientists to monitor neural stem cells that might help repair neurological damage
Making a mark on mitochondria
17 Feb 2015A fluorescent probe for labeling mitochondria helps scientists study fat-burning brown adipose tissue
Taking advantage of defects in splicing
3 Dec 2013A newly discovered early-warning system triggers cellular suicide when a critical RNA editing system breaks down