Cross-dimensional gene exploration8 Mar 2023
A new computational tool gives scientists a 3D view of the gene expression landscape in tissues to better track disease progression and design targeted drugs.
Deciphering asthma’s genetic puzzle14 Jan 2022
A new link between gene variations in immune cells and allergic reactions explains why some individuals are more prone to developing asthma.
A closer look into the genetics of blindness5 Dec 2021
Using whole-exome sequencing, scientists have identified a gene likely linked to a common eye disorder that can lead to blindness in the elderly.
Ending the diagnostic odyssey20 Oct 2021
Asian patients with suspected but undiagnosed rare genetic diseases could get answers sooner thanks to next-generation sequencing technologies.
Catering to the quirks of lung cancer in East Asians24 Dec 2020
A large genetic study has identified distinct features of lung cancer in East Asians, which which could improve prediction and treatment outcomes.
Genetic clues lead to the identification of Jamuar Syndrome16 Oct 2020
An international consortium gives a debilitating childhood disorder a name and a genetic cause.
A fatal flaw in the immune system28 Sep 2020
Clinicians and scientists have discovered a rare mutation that impairs the immune system, and are using their findings to devise treatment strategies
Bioinformatics: At the forefront, behind the scenes4 Sep 2020
Sebastian Maurer-Stroh shares how bioinformatics has enabled Singapore to respond quickly to COVID-19 and will continue to play an important role in ongoing surveillance.
The mutation making COVID-19 milder24 Aug 2020
Scientists at A*STAR have found that a mutation in SARS-CoV-2 called ∆382 leads to milder clinical outcomes, with implications for COVID-19 treatments and vaccines.
The COVID-19 outliers16 Jul 2020
An international genetics consortium seeks to unravel the mystery of why COVID-19 infection is silent in some cases and lethal in others.
Rethinking breast cancer risk31 Mar 2020
Jingmei Li is developing a risk scoring system for breast cancer that could help clinicians formulate better screening programs to catch the disease in its early stages.
Asian genomes in the spotlight24 Feb 2020
A*STAR scientists have created the world’s largest multi-ethnic Asian genetic database to further biomedical research and shed light on the origins of three major ethnic groups in the region.