Genetics

An integrated sequencing platform successfully uncovers a hidden genomic variant of a rare liver disease, sparking new precision medicine options.

The SG-NEx project delivers rich long-read RNA sequencing data that capture subtle differences in gene activity, opening avenues for discovering novel biomarkers in health and disease.

An early childhood study reveals that some genetic roots of obesity may also link to language-related neurodevelopment.

A new chemical testing platform harnesses colour- and light-producing genes from wildlife to speed the search for promising RNA-based therapeutics.

A comprehensive genomic map reveals how certain genes regulate key cells in blood sugar control, offering new insights for future diabetes treatments.

A new deep learning method outperforms traditional methods for identifying genetic mutations from DNA sequences and can be a valuable tool for improved cancer diagnostics.

Scientists discover genes encoding colours, scents and bioactive compounds in the genome of Papilionanthe Miss Joaquim, Singapore’s National Flower.

Researchers have discovered a molecular pathway in colorectal cancer cells that leads to uncontrolled division, creating an avenue for more targeted therapies.

A new computational tool gives scientists a 3D view of the gene expression landscape in tissues to better track disease progression and design targeted drugs.

A new link between gene variations in immune cells and allergic reactions explains why some individuals are more prone to developing asthma.

Using whole-exome sequencing, scientists have identified a gene likely linked to a common eye disorder that can lead to blindness in the elderly.

Asian patients with suspected but undiagnosed rare genetic diseases could get answers sooner thanks to next-generation sequencing technologies.