Genetics

A new deep learning method outperforms traditional methods for identifying genetic mutations from DNA sequences and can be a valuable tool for improved cancer diagnostics.

Scientists discover genes encoding colours, scents and bioactive compounds in the genome of Papilionanthe Miss Joaquim, Singapore’s National Flower.

Researchers have discovered a molecular pathway in colorectal cancer cells that leads to uncontrolled division, creating an avenue for more targeted therapies.

A new computational tool gives scientists a 3D view of the gene expression landscape in tissues to better track disease progression and design targeted drugs.

A new link between gene variations in immune cells and allergic reactions explains why some individuals are more prone to developing asthma.

Using whole-exome sequencing, scientists have identified a gene likely linked to a common eye disorder that can lead to blindness in the elderly.

Asian patients with suspected but undiagnosed rare genetic diseases could get answers sooner thanks to next-generation sequencing technologies.

A large genetic study has identified distinct features of lung cancer in East Asians, which which could improve prediction and treatment outcomes.

An international consortium gives a debilitating childhood disorder a name and a genetic cause.

Clinicians and scientists have discovered a rare mutation that impairs the immune system, and are using their findings to devise treatment strategies

Sebastian Maurer-Stroh shares how bioinformatics has enabled Singapore to respond quickly to COVID-19 and will continue to play an important role in ongoing surveillance.

Scientists at A*STAR have found that a mutation in SARS-CoV-2 called ∆382 leads to milder clinical outcomes, with implications for COVID-19 treatments and vaccines.