Genome Institute of Singapore (GIS)

A platform for rapidly profiling mutations and gene expression offers valuable insights into cancer biology

State-of-the-art single-cell RNA sequencing technologies shed light on the mechanisms through which cancer cells become resistant to tumor-treating drugs

Thermal stress elicits genomic changes that can make cancer cells resistant to chemotherapy

A deeper understanding of chromosome capping could improve therapies for both cancer and aging

A dual-function protein switch can be tweaked to improve the effectiveness of cellular reprogramming

A high-throughput screening technique detects special messenger RNA molecules that sense and respond to environmental signals

By using nanosized charged polymer balls to attack tumors directly rather than carry drugs, researchers have found a way to overcome drug resistance

Assay combines microfluidics and next-generation sequencing to reveal more mutations than existing targeted gene tests

Stem cells that can produce both major lung tissue types have been isolated and can now repair the damaged lungs of mice

Genetic and epigenetic testing of samples from people with cellular changes to the stomach lining could help predict their risk of developing cancer

Machine learning helps locate dozens of mutations statistically linked to gastric cancer in non-coding DNA regions

Virus-targeting white blood cells in tumors offer intriguing insights into responsiveness to immunotherapy