Genome Institute of Singapore (GIS)
Single-cell insights towards precision cancer care
25 Mar 2024Researchers performed a comprehensive genetic sequencing of individual tumour cells to refine existing colorectal cancer classifications.
Connecting the dots
8 Mar 2024By contributing deep insights to Singapore’s innovation ecosystem, A*STAR initiatives are helping to build strategic relationships with international partners and bridge the gaps in local capabilities.
Gene editing cuts to the chase
6 Feb 2024A programmable gene editing tool targets and eliminates a rapidly mutating RNA virus responsible for hand, foot and mouth disease.
Beyond skin deep
4 Jan 2024From molecular methods to advanced optics, scientists are combining techniques and expertise from diverse disciplines to transform skin health research and fortify the body’s outermost barrier.
Baring breast cancer’s genetic dependencies
2 Jan 2024Researchers reveal how disrupting a key genetic control mechanism can significantly hinder the progression and spread of an aggressive and difficult-to-treat form of breast cancer.
When a chromatin safekeeper drops its guard
26 Dec 2023A*STAR researchers identified the mechanism behind how a common gene mutation in kidney cancer impacts chromatin remodelling and drives tumour development, opening up new possibilities for therapeutic interventions.
Reading hidden notes on genetic molecules
13 Dec 2023A new computational tool accurately predicts RNA modifications from sequencing data, allowing researchers to study and develop novel therapies for complex diseases such as cancer.
A deep dive into cancer’s big data
1 Dec 2023A new deep learning method outperforms traditional methods for identifying genetic mutations from DNA sequences and can be a valuable tool for improved cancer diagnostics.
Brain and body, intertwined
31 Oct 2023Through close collaborations across scientific disciplines, A*STAR drives new discoveries in neurometabolism and its potential therapeutic applications.
Decrypting the breast cancer code
25 Oct 2023Researchers extract insights from large databases of genetic and clinical information in a bid to develop more robust, data-driven breast cancer screening frameworks.
Hidden threats from benign colonisers
3 Oct 2023Genomic profiles of the human gut microbiome reveal the hidden impacts of asymptomatic, antibiotic-resistant bacterial infections, as well as potential solutions for their reversal.
Keeping pace with evasive viruses
19 Sep 2023With near-real-time genomic monitoring, researchers catch emergent, treatment-evading SARS-CoV-2 mutations in immunocompromised patients with chronic infections.