Genome Institute of Singapore (GIS)

Through innovative technologies and deep biological insights, A*STAR research institutes and ecosystem partners aim to enhance the healthspan of Asia’s ageing populations.

A*STAR researchers develop a new method to study RNA’s intricate folding patterns within a single cell, revealing fresh insights into how cells develop and function.

Bambu, a new computational tool for analysing genetic data, effectively identifies and quantifies complex gene patterns.

Advanced DNA sequencing technologies reveal little trace of native microbial communities in healthy human blood, challenging recent claims to the contrary.

The A*STAR researchers in NRF Singapore’s class of 2024.

Researchers identify predictive immune ‘signatures’ in liver cancer patients that can help tailor and improve the success rates of combined immunotherapy and radiotherapy.

Researchers performed a comprehensive genetic sequencing of individual tumour cells to refine existing colorectal cancer classifications.

By contributing deep insights to Singapore’s innovation ecosystem, A*STAR initiatives are helping to build strategic relationships with international partners and bridge the gaps in local capabilities.

A programmable gene editing tool targets and eliminates a rapidly mutating RNA virus responsible for hand, foot and mouth disease.

From molecular methods to advanced optics, scientists are combining techniques and expertise from diverse disciplines to transform skin health research and fortify the body’s outermost barrier.

Researchers reveal how disrupting a key genetic control mechanism can significantly hinder the progression and spread of an aggressive and difficult-to-treat form of breast cancer.

A*STAR researchers identified the mechanism behind how a common gene mutation in kidney cancer impacts chromatin remodelling and drives tumour development, opening up new possibilities for therapeutic interventions.