Genome Institute of Singapore (GIS)

A large genetic study has identified distinct features of lung cancer in East Asians, which which could improve prediction and treatment outcomes.

From genomics to gene editing and cancer research, the A*STAR winners of the 2020 President’s Science and Technology Awards and Young Scientist Awards are blazing the trail in biological research.

A genetic discovery reveals why some aggressive carcinomas do not respond to standard treatment and suggest a more effective option.

Exploiting a mutation in a key tumor-fighting protein may provide a new opportunity to treat aggressive lung cancers.

Researchers have pieced together a series of molecular events that trigger the progression of chronic myeloid leukemia to its acute phase—the ‘blast crisis.’

A study implicates novel genetic risk factors in a rare and aggressive lymphoma affecting Asian populations.

An extensive survey of pathogens in hospital environments finds distinct microbial communities enriched for multidrug resistance.

A large-scale genome study suggests that Alzheimer’s and an eye disorder called glaucoma share a common disease development pathway.

A*STAR scientists have uncovered a novel surface marker that identifies stem cells and potential cancer stem cells in the distal stomach.

A*STAR scientists have identified drug compounds that could potentially eradicate an aggressive form of liver cancer by targeting a metabolic vulnerability induced by the SALL4 oncogene.

Jingmei Li is developing a risk scoring system for breast cancer that could help clinicians formulate better screening programs to catch the disease in its early stages.

A*STAR scientists have created the world’s largest multi-ethnic Asian genetic database to further biomedical research and shed light on the origins of three major ethnic groups in the region.