A*STAR Genome Institute of Singapore (A*STAR GIS)

The SG-NEx project delivers rich long-read RNA sequencing data that capture subtle differences in gene activity, opening avenues for discovering novel biomarkers in health and disease.

A comprehensive study across different life stages unveils new insights into the roles of the skin microbiome and lipidome in impacting skin health.

A machine learning model called Fragle helps detect cancer and spot signs of relapse by quantifying DNA fragments in the blood.

In recognition of their research excellence, leadership and impact both locally and globally, ten leading A*STAR researchers have been awarded the A*STAR Distinguished Fellowship and Fellowships.

From biomedical research to generative AI models, scientific progress depends on strong ethical standards that maintain integrity, transparency and accountability.

A groundbreaking multinational atlas of the body’s frontline defenders reveals hidden variations that could enhance precision health efforts worldwide.

A new ‘liquid lipid’ approach that penetrates the nose’s mucus barrier could lead to needle-free, nasal spray-based mRNA vaccines.

Targeting a key gene can help prevent the body’s immune fighters from wearing out when attacking tumour cells, offering a new treatment strategy against cancer.

A*STAR researchers discover how subtle changes to a packaging component of mRNA vaccines can boost their efficacy and safety.

Integrating molecular insights from several omics profiling approaches, A*STAR research initiatives are deepening our understanding of human physiology and unearthing new diagnostic and therapeutic opportunities.

From innovative medical devices to advanced manufacturing partnerships, the work of A*STAR recipients of the 2024 President’s Science and Technology Awards exemplify the importance of translating research into clinical and commercial outcomes.

Scientists identify a new, distinct group of the deadly yeast Candida auris, and urge the expansion of global surveillance efforts.