Genome Institute of Singapore (GIS)

A genetic cause for anencephaly, a common neural tube defect found in developing fetuses, has been identified for the first time.

Understanding the impact of antibiotics on both infants and adults could help restore the delicate balance of the gut microbiome.

Differences in the skin microbiome could reveal clues as to why some cases of atopic dermatitis are more severe than others.

Keystone bacterial species help to restore gut microbial diversity after treatment with antibiotics, paving the way for improved prebiotic and probiotic formulations.

A novel genomic biomarker may help to meet the demand for donor mesenchymal stem cells in regenerative medicine.

Being able to distinguish between different types of macrophages in the brain could shed light on inflammatory diseases such as Alzheimer’s.

The Epstein-Barr virus can cause epigenetic changes that persist even after the infection has been cleared, highlighting why prevention is better than cure when it comes to gastric cancer.

A large genetic study has identified distinct features of lung cancer in East Asians, which which could improve prediction and treatment outcomes.

From genomics to gene editing and cancer research, the A*STAR winners of the 2020 President’s Science and Technology Awards and Young Scientist Awards are blazing the trail in biological research.

A genetic discovery reveals why some aggressive carcinomas do not respond to standard treatment and suggest a more effective option.

Exploiting a mutation in a key tumor-fighting protein may provide a new opportunity to treat aggressive lung cancers.

Researchers have pieced together a series of molecular events that trigger the progression of chronic myeloid leukemia to its acute phase—the ‘blast crisis.’