Genome Institute of Singapore (GIS)
A*STAR scientists have created the world’s largest multi-ethnic Asian genetic database to further biomedical research and shed light on the origins of three major ethnic groups in the region.
A*STAR scientists have devised an algorithm for accurately assembling genomes, paving the way for in-depth analysis of microbial communities in the human gut.
A*STAR researchers demonstrate how the expression of genes from alternative gene promoters is associated with lower cancer survival in patients.
A gene variant more common among East Asians is responsible for milder symptoms and better outcomes during hepatitis B infection.
Short- and long-range interactions that give structure to virus genomes also influence virus replication and infectiousness.
Disruption of the methionine cycle in tumor-initiating cells disarms their tumorigenic capabilities, researchers say.
A*STAR scientists have identified two Epstein-Barr virus strains associated with a high risk of causing nasopharyngeal carcinoma.
A platform for rapidly profiling mutations and gene expression offers valuable insights into cancer biology
State-of-the-art single-cell RNA sequencing technologies shed light on the mechanisms through which cancer cells become resistant to tumor-treating drugs
Thermal stress elicits genomic changes that can make cancer cells resistant to chemotherapy
A deeper understanding of chromosome capping could improve therapies for both cancer and aging