Immunology
Flipping the switch on gut inflammation
26 Oct 2021A newly-discovered role for an immune regulator in T cells may help unravel the molecular basis of inflammatory bowel disease and serve as a promising therapeutic target.
Not all antibodies are created equal
10 Sep 2021Some neutralizing antibodies against SARS-CoV-2 may heighten lung tissue damage from COVID-19, an A*STAR study finds.
Memories of our first microbial encounters
8 Sep 2021Live bacterial strains present in fetal tissues may help lay the cornerstones of early and potentially life-long immunity.
Unraveling the complexity of immune cells
28 Jul 2021By tapping into the inner workings of cells, Jinmiao Chen uses novel analytical technologies to understand why immune responses vary greatly among individuals.
Deciphering a wound healing paradox
4 Jun 2021A*STAR researchers identify a novel mechanism in which an inflammatory protein heals wounds in healthy individuals but has the opposite effect in diabetics.
Getting granular about granulocyte differentiation
2 Jun 2021Controlling the delicate balance between immune cells called granulocytes and monocytes could make the difference between a healthy immune response and life-threatening sepsis.
Tumors hide by mimicking fetal characteristics
26 Apr 2021Liver tumors gain immune tolerance by activating cellular mechanisms involved in fetal development.
Zika’s art of camouflage
21 Apr 2021The mosquito-borne virus dodges immune clearance by cloaking itself in disarmed antibodies.
Striking with precision at liver cancer
9 Apr 2021A new biomarker in liver tumor may help doctors predict how patients respond to immunotherapy.
Turning back the immunological clock
7 Apr 2021The discovery of how aging impacts memory T cells may unlock novel therapeutic targets to boost immune protection in older adults.
Forecasting a (cytokine) storm
29 Mar 2021These novel immune signatures identify patients most at risk for developing severe COVID-19 symptoms.
Scratching the surface of atopic dermatitis
3 Mar 2021Differences in the skin microbiome could reveal clues as to why some cases of atopic dermatitis are more severe than others.