Immunology

A*STAR scientists have found a way to boost the activity of neutrophils, a subset of immune cells, against disease-causing fungi.

By mapping the development trajectory of immune precursor cells, A*STAR scientists showed that plasmacytoid dendritic cells were incorrectly classified in the immune ‘family tree.’ 

Targeted mutagenesis is being used to create live-attenuated vaccines against the chikungunya virus.

A*STAR scientists have found a way to strengthen the immune response to adenovirus infection using engineered antibodies.

A gene variant more common among East Asians is responsible for milder symptoms and better outcomes during hepatitis B infection.

Researchers at A*STAR have developed a method to obtain a holistic view of the identities and proportions of immune cells in patient blood samples.

The antiviral protein Viperin keeps immune cells in check to prevent joint swelling during chikungunya virus infection.

The AllerCatPro analysis workflow helps researchers predict the likelihood of a protein producing an allergic response in people.

Deciphering the immune response in mosquitoes to the O’nyong nyong virus may lead to new broad-spectrum antiviral targets.

Researchers have obtained a high-resolution structure of the RIP2 protein complex and detailed its interactions with other immune proteins.

A*STAR researchers have devised a method to generate a renewable source of mature human Kupffer cells for liver toxicity bioassays.

When parts of a bacteria’s cell wall enter into circulation, its host experiences more severe autoimmune reactions.