Immunology

Could there be a drug that can both treat and protect against COVID-19? The answer may be found in antibody drugs, a promising therapeutic modality against the coronavirus.

Two coronavirus experts suggest that the best way to control an outbreak may be to first understand viral biology and behavior in animals and humans.

Scientists at A*STAR have found that a mutation in SARS-CoV-2 called ∆382 leads to milder clinical outcomes, with implications for COVID-19 treatments and vaccines.

Tipped off by artificial intelligence, a research team is testing whether a rheumatoid arthritis drug could be repurposed as a COVID-19 treatment.

Single-cell genomic technology is providing fresh perspectives on the origins of microglia, ancient immune sentinels found in the brain.

Researchers at A*STAR have uncovered a new role for a subset of immune cells in HIV infection and transmission.

A*STAR scientists can now classify immune cell populations with greater precision thanks to a machine-learning algorithm.

A*STAR scientists have identified a molecular marker for tracing the origins of immune cells that reside in tissues and organs.

A*STAR researchers uncover how bacteria and the immune system generate alarm behavior in fish.

A*STAR scientists have found a way to boost the activity of neutrophils, a subset of immune cells, against disease-causing fungi.

By mapping the development trajectory of immune precursor cells, A*STAR scientists showed that plasmacytoid dendritic cells were incorrectly classified in the immune ‘family tree.’ 

Targeted mutagenesis is being used to create live-attenuated vaccines against the chikungunya virus.