Immunology

A newly-discovered role for an immune regulator in T cells may help unravel the molecular basis of inflammatory bowel disease and serve as a promising therapeutic target.

Some neutralizing antibodies against SARS-CoV-2 may heighten lung tissue damage from COVID-19, an A*STAR study finds.

Live bacterial strains present in fetal tissues may help lay the cornerstones of early and potentially life-long immunity.

By tapping into the inner workings of cells, Jinmiao Chen uses novel analytical technologies to understand why immune responses vary greatly among individuals.

A*STAR researchers identify a novel mechanism in which an inflammatory protein heals wounds in healthy individuals but has the opposite effect in diabetics.

Controlling the delicate balance between immune cells called granulocytes and monocytes could make the difference between a healthy immune response and life-threatening sepsis.

Liver tumors gain immune tolerance by activating cellular mechanisms involved in fetal development.

The mosquito-borne virus dodges immune clearance by cloaking itself in disarmed antibodies.

A new biomarker in liver tumor may help doctors predict how patients respond to immunotherapy.

The discovery of how aging impacts memory T cells may unlock novel therapeutic targets to boost immune protection in older adults.

These novel immune signatures identify patients most at risk for developing severe COVID-19 symptoms.

Differences in the skin microbiome could reveal clues as to why some cases of atopic dermatitis are more severe than others.