Institute of Medical Biology (IMB)
A*STAR scientists have identified stem cells required for successful embryo implantation during pregnancy.
Bortezomib, a drug that inhibits the ‘waste disposal system’ in animal cells, could treat cancer by indirectly stabilizing a protein that suppresses cell division.
Researchers at A*STAR have combined two superresolution microscopy techniques to observe structural protein dynamics inside cells.
A protein named GATA6 is key to the development of a normal pancreas in humans.
Researchers have obtained a high-resolution structure of the RIP2 protein complex and detailed its interactions with other immune proteins.
By turning a pathogenic yeast into an immunity-conferring symbiont, a team of A*STAR researchers is unraveling mysteries behind gut evolution and universal vaccines
The size and composition of protein-binding sugars in the extracellular matrix play a crucial role in bone repair
Thermal stress elicits genomic changes that can make cancer cells resistant to chemotherapy
A carefully defined balance of biomolecular signals stimulates healing by setting skin cells into motion
A deeper understanding of chromosome capping could improve therapies for both cancer and aging
Assay combines microfluidics and next-generation sequencing to reveal more mutations than existing targeted gene tests