Institute of Medical Biology (IMB)
Clinicians and scientists have discovered a rare mutation that impairs the immune system, using their findings to devise treatment strategies
A*STAR scientists have uncovered a novel surface marker that identifies stem cells and potential cancer stem cells in the distal stomach.
By enhancing stem cell proliferation, this newly developed heparan sulphate glycosaminoglycan bio-additive lowers the barriers to regenerative medicine.
Modifying how embryonic stem cells use sugar can switch them into a totipotent state, A*STAR researchers say.
DNA damage associated with premature aging in Hutchinson-Gilford Progeria Syndrome can be prevented if the abnormal protein progerin is removed before DNA replication.
A protein called SUN1 enables muscle cells to respond to mechanical forces by modifying microRNA levels, say A*STAR researchers.
A*STAR scientists have identified stem cells required for successful embryo implantation during pregnancy.
Bortezomib, a drug that inhibits the ‘waste disposal system’ in animal cells, could be used to suppress cell division in cancer.
Researchers at A*STAR have combined two superresolution microscopy techniques to observe structural protein dynamics inside cells.
A protein named GATA6 is key to the development of a normal pancreas in humans.
Researchers have obtained a high-resolution structure of the RIP2 protein complex and detailed its interactions with other immune proteins.