Institute of Medical Biology (IMB)

Multidisciplinary efforts across A*STAR are paving the way toward Singapore’s precision medicine vision.

Nuevocor, an A*STAR spin-off company, is designing novel therapies to target the genetic causes of heart diseases, bringing basic research to clinical impact.

The mysterious trigger of the NLRP1 inflammasome sensor has finally been identified: a protease found in the common cold-causing human rhinovirus tells our body that it has been invaded.

For the first time, researchers have generated lab-grown livers that have functioning bile canaliculi, an important step towards modeling complex liver diseases.

A genetic cause for anencephaly, a common neural tube defect found in developing fetuses, has been identified for the first time.

A novel genomic biomarker may help to meet the demand for donor mesenchymal stem cells in regenerative medicine.

Flower-like ‘rosettes’ may help malaria parasites evade the body’s immune defences.

A microRNA called miR-355 has been identified as the key regulator of skin cell differentiation in patients with atopic dermatitis.

Researchers at A*STAR have discovered how a class of small proteins is essential for metabolism.

An international consortium gives a debilitating childhood disorder a name and a genetic cause.

Clinicians and scientists have discovered a rare mutation that impairs the immune system, and are using their findings to devise treatment strategies

A*STAR scientists have uncovered a novel surface marker that identifies stem cells and potential cancer stem cells in the distal stomach.