Institute of Medical Biology (IMB)
Researchers at A*STAR have combined two superresolution microscopy techniques to observe structural protein dynamics inside cells.
A protein named GATA6 is key to the development of a normal pancreas in humans.
Researchers have obtained a high-resolution structure of the RIP2 protein complex and detailed its interactions with other immune proteins.
By turning a pathogenic yeast into an immunity-conferring symbiont, a team of A*STAR researchers is unraveling mysteries behind gut evolution and universal vaccines
The size and composition of protein-binding sugars in the extracellular matrix play a crucial role in bone repair
Thermal stress elicits genomic changes that can make cancer cells resistant to chemotherapy
A carefully defined balance of biomolecular signals stimulates healing by setting skin cells into motion
A deeper understanding of chromosome capping could improve therapies for both cancer and aging
Assay combines microfluidics and next-generation sequencing to reveal more mutations than existing targeted gene tests
A microfluidic organ-on-a-chip device combines skin culture and testing capabilities to offer a substitute to animal testing
Genetic and epigenetic testing of samples from people with cellular changes to the stomach lining could help predict their risk of developing cancer
Deep data analytics drive the development of a technique
that sheds light on drug action by monitoring the dynamics of thousands of protein complexes simultaneously
within intact cells