Institute of Molecular and Cell Biology (IMCB)
Targeted mutagenesis is being used to create live-attenuated vaccines against the chikungunya virus.
Estimation plots provide researchers with a more complete picture of the significance of their results than traditional P values, say A*STAR scientists.
By interfering with the production and downstream activity of a molecule called Agrin in tumors, scientists can stop the sprouting of blood vessels that promote cancer progression.
Researchers at A*STAR have invented a biodegradable thermogel that mimics the clear, gelatinous substance called vitreous in the eye.
Mutations in the gene HNF4A impair liver and pancreas development, indicating that maturity-onset diabetes of the young starts much earlier than initially thought.
An automated machine learning system for analyzing leg movements in fruit flies is helping A*STAR researchers shed light on how neurodegenerative diseases develop.
In times of stress, cancer cells move a protein normally found inside the cell to the cell surface, making it accessible to antibodies for immunotherapy.
Disruption of the methionine cycle in tumor-initiating cells disarms their tumorigenic capabilities, researchers say.
A*STAR researchers have devised a method that can detect and distinguish closely related flaviviruses with 100 percent accuracy.
Proteomics expert Ruedi Aebersold discusses the use of multiplex targeted mass spectrometry for one-shot flavivirus diagnosis.
Researchers have obtained a high-resolution structure of the RIP2 protein complex and detailed its interactions with other immune proteins.