A*STAR Institute of Molecular and Cell Biology (A*STAR IMCB)

A*STAR researchers develop a smarter delivery system for mRNA vaccines that boosts their targeting abilities and biological safety.

Region-specific stem cells may not only act as starting points for colorectal cancer, but also offer new clues for early detection and treatment.

As the Chairman of Singapore’s lead R&D public sector agency, Chorh Chuan Tan outlines A*STAR’s strategic role within a new phase of national strategic priorities in research, innovation and enterprise.

This year’s L’Oréal-UNESCO For Women in Science (Singapore) Awards programme recognises three women scientists for their exceptional contributions to neuroscience, infectious diseases and RNA therapeutics.

A unique RNA structure shared across SARS-CoV-2 variants may contribute to viral fitness, offering a potential target for new antiviral treatments.

Comparing hypothalamic networks in zebrafish and mice reveals evolutionarily conserved neuronal pathways that regulate appetite across vertebrates.

A*STAR researchers take a layered approach to create fibrous alternative meat products that mimic the sensory profiles of the real deal.

Disrupting the binding of a key protein pair in immune cells could help avert deadly allergic responses.

Self-looping molecules could be the key to unlocking the potential of RNA-based vaccines and therapies.

Whether combating global viral threats or advancing next-generation telecommunications, the A*STAR winners of the 2025 President’s Science and Technology Awards showcase the talent and drive at the foundations of world-class research excellence.

At the core of A*STAR’s research mission, Kian Teik Beh underscores the importance of prioritising real-world needs and bridging discovery with deployment in the clinic, industry and marketplace.

An integrated sequencing platform successfully uncovers a hidden genomic variant of a rare liver disease, sparking new precision medicine options.