Metabolism

In lung cancer, tumour-initiating cells harness ketones as an alternative energy source during nutrient stress, but this flexibility also leads to a therapeutic vulnerability.

A first-in-Asia study reveals how legume-rich diets trigger shifts in the gut microbiome that boost metabolic health in prediabetic adults.

A*STAR scientists have identified drug compounds that could potentially eradicate an aggressive form of liver cancer by targeting a metabolic vulnerability induced by the SALL4 oncogene.

Insights into the molecular changes in regenerating liver cells may reveal ways to help patients recover from surgery or disease

Tumor growth in a mouse model of lung cancer is
reduced using an RNA-based therapeutic that inhibits a metabolic pathway in tumor-initiating
cells

The age-old search for a cure for hair loss may be close to an end

A rare mutation causes severe growth retardation and spine malformation in humans and mice

Immune cells localized near pancreatic cancer cells
have an altered metabolism and could be involved in promoting the spread of cancer
to other organs

A new imaging technique that produces metabolic maps of brain activity may improve disease diagnosis and reduce patient exposure to radiation

Blood vessel development in the pancreas is regulated by the signaling molecule STAT3