Metabolism
Exposing the weakness of a tough drug target
1 Jun 2020A*STAR scientists have identified drug compounds that could potentially eradicate an aggressive form of liver cancer by targeting a metabolic vulnerability induced by the SALL4 oncogene.
Metabolic remodeling during regeneration
5 Mar 2019Insights into the molecular changes in regenerating liver cells may reveal ways to help patients recover from surgery or disease
Targeting the root of the problem
22 Mar 2018Tumor growth in a mouse model of lung cancer is
reduced using an RNA-based therapeutic that inhibits a metabolic pathway in tumor-initiating
cells
Getting to the root of hair loss
28 Jan 2018The age-old search for a cure for hair loss may be close to an end
Of mice and men
13 Dec 2017A rare mutation causes severe growth retardation and spine malformation in humans and mice
Altered metabolism extends beyond cancer cells
8 May 2017Immune cells localized near pancreatic cancer cells
have an altered metabolism and could be involved in promoting the spread of cancer
to other organs
Imaging the brain’s energy usage
21 Jan 2014A new imaging technique that produces metabolic maps of brain activity may improve disease diagnosis and reduce patient exposure to radiation
Striking a balance
27 Apr 2010Blood vessel development in the pancreas is regulated by the signaling molecule STAT3
