Microglia

A new analytical platform reveals signature changes in immune cells of the brain during aging and neurodegenerative conditions such as Alzheimer’s disease.

Being able to distinguish between different types of macrophages in the brain could shed light on inflammatory diseases such as Alzheimer’s.

The effect of gut microbes
on the mouse brain depends on both sex and stage of development

A new method for making specialized immune cells
from stem cells offers a tool for modeling inflammatory diseases in the lab 

Macrophages
are shown to originate from two distinct sources during the earliest stages of
development in the embryo

Langerhans cells, specific immune cells in the skin, migrate to their final destination in multiple waves at different stages of embryonic development

A large part of the development of brain immune cells takes place at the embryonic stage