Pancreas
A closer look at metformin in maternal diabetes
25 Jan 2022New data suggest that metformin administered to pregnant mothers may have unintended effects on the fetus, prompting the need for further assessment of the drug’s risk-benefit ratio.
Opening the cellular gates to glucose
2 Jul 2021Low levels of sugar entering into pancreatic cells may be the culprit behind insulin secretion defects in early-onset diabetes.
Getting to the roots of early-onset diabetes
23 Aug 2019Mutations in the gene HNF4A impair liver and pancreas development, indicating that maturity-onset diabetes of the young starts much earlier than initially thought.
Directing cell fates
14 Jul 2015A master gene determines whether cells become pancreatic or liver cells
A roadmap for pure organ cells
17 Jun 2014A new strategy minimizes the cellular contaminants that usually plague the differentiation of pluripotent stem cells