Sequencing

A*STAR researchers developed an algorithm that enables more accurate assembly of genomic sequences to help us better understand the molecular variations underlying health and disease.

The SG-NEx project delivers rich long-read RNA sequencing data that capture subtle differences in gene activity, opening avenues for discovering novel biomarkers in health and disease.

Bambu, a new computational tool for analysing genetic data, effectively identifies and quantifies complex gene patterns.

Advanced DNA sequencing technologies reveal little trace of native microbial communities in healthy human blood, challenging recent claims to the contrary.

Researchers performed a comprehensive genetic sequencing of individual tumour cells to refine existing colorectal cancer classifications.

With near-real-time genomic monitoring, researchers catch emergent, treatment-evading SARS-CoV-2 mutations in immunocompromised patients with chronic infections.

Dr. Sydney Brenner, the visionary molecular biologist and Nobel laureate who turned a humble soil worm into one of the most-studied organisms in biology, passed away on April 5, 2019 in Singapore. He was 92.

Analyzing gene activity in single cells offers a
clearer view of bowel cancer

Smarter software allows researchers to generate higher-quality data from an exciting new DNA sequencing technology