A*STAR Singapore Immunology Network (A*STAR SIgN)
Back to the basics of hunger circuits
3 Mar 2026Comparing hypothalamic networks in zebrafish and mice reveals evolutionarily conserved neuronal pathways that regulate appetite across vertebrates.
Releasing the brakes on liver cancer treatment
23 Feb 2026An anti-hypertension drug could potentially be repurposed as a more affordable treatment for liver cancer.
A milky gut trainer
13 Feb 2026Breast milk is supercharged with antibodies that promote healthy gut immunity in babies.
Protein partner break-up relieves allergies
5 Feb 2026Disrupting the binding of a key protein pair in immune cells could help avert deadly allergic responses.
Neutrophils fill the gaps in skin defence
21 Nov 2025A deep dive into the skin barrier uncovers the critical role immune cells play in structural reinforcement and wound healing.
Driving science to new horizons
19 Nov 2025In recognition of their research excellence, leadership and impact both locally and globally, ten leading A*STAR researchers have been awarded the A*STAR Distinguished Fellowship and Fellowships.
Gluing together layers of molecular insights
29 May 2025A new spatial multi-omics tool merges different levels of biological data from the same tissue sample to better differentiate finer details at different health states.
Microbial neighbours keep golden years shining
22 Apr 2025A large-scale gut microbiome study in elderly Singaporeans reveals new insights into the role of our resident microbes in healthy ageing.
Deconstructing the esophagus cell by cell
3 Mar 2025Researchers uncovered how specialised stem cells act as building blocks for the esophagus, shaping its development and offering insights into treating related diseases.
Taming T cells to douse eczema’s flare
22 Nov 2024A*STAR researchers discovered a potential new treatment for severe eczema by targeting a protein that regulates immune cell activity.
Reinforcing frontline defences against variants
14 Nov 2024Antibodies in mucous membranes may be key in protecting against SARS-CoV-2 variants, pointing to the need for COVID-19 vaccines that target these antibody responses.
Steadying antibodies against variant surges
23 Oct 2024A high-resolution study of SARS-CoV-2 antibodies revealed how they neutralise variants and reduce the impact of spike protein mutations.