Singapore Immunology Network (SIgN)

A three-dimensional liver organoid model for studying dormant malaria parasites may pave the way for better antimalarial drugs.

By mapping the development trajectory of immune precursor cells, A*STAR scientists showed that plasmacytoid dendritic cells were incorrectly classified in the immune ‘family tree.’ 

Targeted mutagenesis is being used to create live-attenuated vaccines against the chikungunya virus.

A*STAR scientists have found a way to strengthen the immune response to adenovirus infection using engineered antibodies.

A gene variant more common among East Asians is responsible for milder symptoms and better outcomes during hepatitis B infection.

Researchers at A*STAR have developed a method to obtain a holistic view of the identities and proportions of immune cells in patient blood samples.

Different forms of the protein HNF4ɑ can pair up to influence diverse processes ranging from development to diabetes, study shows.

A*STAR researchers have identified four peptide sequences that distinguish the Zika virus from other flaviviruses, with implications for diagnostics and vaccine development.

The antiviral protein Viperin keeps immune cells in check to prevent joint swelling during chikungunya virus infection.

Deciphering the immune response in mosquitoes to the O’nyong nyong virus may lead to new broad-spectrum antiviral targets.

When parts of a bacteria’s cell wall enter into circulation, its host experiences more severe autoimmune reactions.

A subset of skin-resident immune cells secrete the protein VEGFα to help mount a robust response to bacterial invasion.