Singapore Immunology Network (SIgN)

Researchers discover key differences in the skin’s natural flora between healthy adults and those with genetic dry skin diseases.

Researchers discover that circadian rhythms control immune responses and may affect how our skin’s immune system responds to allergies.

Researchers develop a protocol to boost the effectiveness of and reduce the risk of potential side effects for T cell cancer therapies.

A novel tissue-profiling approach provides new insights into the mechanisms of fatal COVID-19 by analysing
different molecules and cell populations within organs.

New associations between COVID-19 and immune responses in cancer patients reveal potential inroads to fighting tumours.

Inactivated COVID-19 vaccines could be an equally potent alternative for people with allergic sensitivities to mRNA-based vaccines.

Researchers unravel a complex inflammatory pathway involved in severe COVID-19 infection and identify a therapeutic mechanism to reverse it.

A new analytical platform reveals signature changes in immune cells of the brain during aging and neurodegenerative conditions such as Alzheimer’s disease.

An analysis of cellular immune responses reveals that mixing COVID-19 vaccines and boosters may offer enhanced protection for at-risk populations.

Booster shots with COVID-19 mRNA outperformed inactivated virus by eliciting stronger antibody responses to the Omicron variant.

Drug-resistant malarial parasites form flower-like structures to shield themselves from attack by antimalarial drugs and the immune system.

A*STAR scientists decipher how a stem cell-based treatment stops the uncontrolled inflammation associated with severe COVID-19 cases.