Highlights
Cancer Biology
Sweet serendipity unveils anticancer strategy
29 November 2019A better understanding of the way sugar units are attached to the surface proteins of cancer cells may help to improve targeted cancer treatments, A*STAR scientists say.
Immunology
The rediscovered origin of an immune cell subtype
29 November 2019By mapping the development trajectory of immune precursor cells, A*STAR scientists showed that plasmacytoid dendritic cells were incorrectly classified in the immune ‘family tree.’
Bioinformatics
How the flu virus hops from one host to another
29 November 2019A*STAR researchers have identified specific sites in the surface protein of influenza viruses that allow the pathogen to adapt to different host organisms.
Cancer Biology
A stabilizing strategy to keep cancer cells in check
29 November 2019Bortezomib, a drug that inhibits the ‘waste disposal system’ in animal cells, could be used to suppress cell division in cancer.
Microbiology
Solving the puzzle of human gut microbiomes
7 November 2019A*STAR scientists have devised an algorithm for accurately assembling genomes, paving the way for in-depth analysis of microbial communities in the human gut.
Drug Manufacturing
Getting drug molecules to fall in line
7 November 2019By controlling the crystallization of pharmaceutical compounds using template surfaces, high quality drugs may be manufactured more cheaply and easily.
Nanotechnology
Precise and printable silicon nanoparticles
7 November 2019Silicon nanoparticles dispersed in solution can be positioned by light and printed onto surfaces, or used in applications such as medical imaging and drug delivery.
Transcriptomics
How promoters predict patient outcomes
7 November 2019A*STAR researchers demonstrate how the expression of genes from alternative gene promoters is associated with lower cancer survival in patients.
Immunology
How to maim a virus without killing it
7 November 2019Targeted mutagenesis is being used to create live-attenuated vaccines against the chikungunya virus.
Robotics
Giving robots the human touch
25 October 2019Researchers at A*STAR have designed a hybrid machine learning model to enhance touch capabilities in robots.
Simulation
Lowering the cost of louver simulations
25 October 2019Simulating building-cooling louvers need not be computationally expensive, say A*STAR researchers.
Statistics
The P value is dead, long live the estimation plot
25 October 2019Estimation plots provide researchers with a more complete picture of the significance of their results than traditional P values, say A*STAR scientists.
Machine Learning
Decoding brain waves with machine learning
16 October 2019A machine learning technique developed by A*STAR scientists could help patients with locked-in syndrome communicate via brain-machine interfaces.
