Researcher

James Chan graduated with a Bachelor of Pharmacy degree and obtained his doctoral degree in Pharmaceutical Science from the National University of Singapore. Subsequently he joined A*STAR in 2018 and established an independent research group in 2020 at both the Singapore Institute of Food and Biotechnology Innovation (SIFBI) and the A*STAR Skin Research Labs (A*SRL). He is currently a Junior Principal Investigator with extensive expertise in pharmacokinetic modelling. In particular, his team integrates digestibility profiles with in vitro absorption, distribution, metabolism and excretion measurements to predict the human pharmacokinetics of orally and topically ingested materials. His current research interests include the modelling the long half-life of PFAS contaminants; prediction of the pharmacokinetics for pharmaceutical, nutritional and consumer care compounds; modelling gut microbiome metabolism; and creating virtual populations that represent vulnerable groups such as pregnant women.