Researcher

Maxime Gasnier is a Senior Scientist in Nick Barker’s laboratory at the A*STAR Institute of Molecular and Cell Biology (A*STAR IMCB). Gasnier obtained his PhD degree from Clermont-Ferrand University, France, under the supervision of Claire Chazaud, where he studied the roles of Dkk1 and Noggin in extraembryonic endoderm differentiation and gained experience in animal and embryo manipulation.

Gasnier’s research focuses on epithelial stem cells in tissue regeneration and cancer. He recently co-authored a study published in Nature Cell Biology describing two novel region-specific mouse colon stem cell drivers and their use in initiating cancer from a stem cell origin. He is currently developing these models to characterise advanced cancer formation and to establish preclinical cancer models.

Previously, during his postdoctoral training at Nicolas Plachta’s laboratory at A*STAR IMCB, Gasnier investigated actin ring formation and expansion in the preimplantation embryo from the 8-cell stage onwards, elucidating their role in establishing the sealing barrier required for blastocyst cavity formation. He has extensive expertise in molecular biology, immunofluorescence, and live-cell imaging.