Advancing synthetic biology across all fronts16 Jul 2021
From expanding the genetic alphabet to uncovering antibiotics hidden in silent genes, A*STAR’s researchers are wielding the tools of synthetic biology to improve our lives in surprising ways.
The dark side of antibiotics and what we can do about it8 Mar 2021
Understanding the impact of antibiotics on both infants and adults could help restore the delicate balance of the gut microbiome.
Clues to childhood obesity lie in our gut30 Nov 2020
Early exposure to antibiotics can disrupt an infant’s gut microbiota and predispose them to childhood obesity, finds an observational study.
Beating bacteria – looking beyond antibiotics15 Jul 2018
A polymer to fight superbugs could help solve the world’s antibiotics crisis.
Gut bacteria affect the brain, even in the womb1 May 2018
The effect of gut microbes
on the mouse brain depends on both sex and stage of development
Triple-threat mixture overcomes drug-resistant lung infections10 Jan 2017
Tailored combinations of antibiotics that kill microbes in different ways are a powerful weapon against drug resistance
A double blast to ward off pneumonia7 Oct 2014
A dry powder inhaler formulation provides excellent protection against pneumonia-causing bacteria
The plastic approach20 Nov 2012
Our antibiotic armory is set to benefit from the development of short-chain synthetic polymers with potent efficacy against multidrug-resistant microbes
Tweaking targets for antibiotics2 Aug 2011
On the back of growing drug resistance, researchers at the A*STAR Institute of Molecular and Cell Biology are exploring new targets to develop effective antibacterial compounds