Cell cycle
Pressing pause on DNA damage
16 Nov 2020A protein known to switch on DNA repair genes also ‘pauses’ the cell cycle in response to DNA damage, A*STAR researchers find.
Making heart tissue ‘beat’
14 Jan 2019The key to efficient production of heart muscle from pluripotent stem cells lies in optimizing the density and replicative state of the starting material
Genetic model refines knowledge of new cancer drugs
29 Nov 2018Mouse studies have revealed more about the mechanisms
behind cancer drugs in trials
Gaps plugged in understanding of cell cycle
15 Aug 2018Similarities between the two gap phases of the
cell cycle indicate a default biochemical program in living cells
Protein prompts a primordial proliferation
13 Jun 2017A regulatory protein ensures that egg precursor cells
boost their numbers during embryonic development
Keeping egg cells on ice
4 Apr 2017Female
fertility is maintained by a newly discovered molecular mechanism that freezes
the cell cycle in egg cells
A human gene atlas for virus replication
7 Mar 2017Genetic screening gives new hope to the fight against a common childhood virus that causes hand, foot and mouth disease
One protein, two important roles
28 Jan 2014A molecular mechanism that directs both cell growth and death via one protein could underpin more efficient cancer therapies
Lifting the brakes on breast cancer growth
12 Feb 2013A protein that represses a critical checkpoint protein for cellular growth helps drive tumor development