Cells

The development of an automated system for analyzing images of the retina will facilitate computer-aided diagnosis of eye diseases

Cancer cells secrete proteins that help them adapt to low-oxygen environments

Scientists are establishing the basic molecular network of a new player involved in protein secretion and clarifying its regulation in mammalian cells

A new breed of microfluidic devices can accelerate drug discovery by making it possible to assess the effects of thousands of drug candidates on ion channels simultaneously

A new bioprocessing system enables large-scale production of heart muscle cells from stem cells

A previously unidentified bacterial protein variant gums up the gears of a last-resort cellular suicide mechanism

Efficient production of glycoprotein drugs to treat anemia and other disorders comes a step closer via genetic engineering

Mammalian genomes display large differences where the regulatory proteins of their embryonic stem cells bind

Inactivation of a protective cellular ‘self-destruct’ mechanism enables cancer cells to grow without restraint

Single-cell gene expression profiling reveals specific genetic programs underlying cell differentiation in pre-implantation mouse embryos

A protein primarily active in the nucleus also operates within the cytoplasm to orchestrate cell movement

More accurate measurements of the forces that bind cells together have been made possible by a new computer model