Dendritic cells
When immune cells aren’t immune after all
3 Jun 2020Researchers at A*STAR have uncovered a new role for a subset of immune cells in HIV infection and transmission.
The rediscovered origin of an immune cell subtype
29 Nov 2019By mapping the development trajectory of immune precursor cells, A*STAR scientists showed that plasmacytoid dendritic cells were incorrectly classified in the immune ‘family tree.’
Targeting TRIM21 for stronger, safer vaccines
16 Oct 2019A*STAR scientists have found a way to strengthen the immune response to adenovirus infection using engineered antibodies.
Battling bacteria that get under the skin
23 May 2019A subset of skin-resident immune cells secrete the protein VEGFα to help mount a robust response to bacterial invasion.
Finding the cells and the signals
29 Aug 2018Clarifying the role of a protein released by immune ‘dendritic’ cells could yield better treatments
Fetal immune system developed, but tolerant
18 Dec 2017More mysteries of the developing immune system have been revealed in a study of fetal
dendritic cells
Explaining adjuvants, the “immunologist’s dirty little secret”
27 Jun 2017Studying
immune response to aluminum salts can explain how these chemicals boost vaccine’s
efficacy
Immune cells upset the kidney
23 Aug 2016Infiltrating self-defense cells provoke kidney failure in a chronic autoimmune disease
Early deciders
1 Jun 2016Precursors to dendritic cells decide what they want to be when they grow
up much earlier than previously thought
White blood cells show their stripes
27 Aug 2013A newly discovered subset of white blood cells in mice and humans could improve treatments for infections and autoimmune diseases
Pinpointing a potential therapeutic target
15 Jan 2013Identification of the subtype of immune cells that is crucial to the onset of cerebral malaria provides a therapeutic starting point
Matching mice and men
23 Oct 2012Recently uncovered human counterparts to a subset of mouse immune cells may enable better vaccination strategies