Developmental biology
Deconstructing the esophagus cell by cell
3 Mar 2025Researchers uncovered how specialised stem cells act as building blocks for the esophagus, shaping its development and offering insights into treating related diseases.
Keeping the beat of life
3 Nov 2021A protein in cilia called CFAP53 is responsible for the distinct beat patterns during embryonic development, researchers say.
A rare glimpse into the pancreas’ origins
1 Nov 2021Induced pluripotent stem cells have helped researchers map the role of the RFX6 gene in a rare congenital disorder known as Mitchell-Riley Syndrome.
A tough choice for embryo cells
25 Jan 2021Keratin, a tough and insoluble fibrous protein, plays a surprising role in determining mouse embryonic cell fate.
Genetic clues lead to the identification of Jamuar Syndrome
16 Oct 2020An international consortium gives a debilitating childhood disorder a name and a genetic cause.
Writing the roadmap for pancreas development
28 Jun 2019A protein named GATA6 is key to the development of a normal pancreas in humans.
Viral remnants are ‘facilitators’ not ‘fossils’
21 Oct 2014Once considered ‘junk’, certain virus-derived genomic elements have now been shown to actively regulate important developmental processes
Unlocking a secret of stem cell stability
5 Nov 2013Proper embryonic development depends on a signaling pathway that helps to preserve stem cell ‘immaturity’
Proteins prove the power of collaboration
18 Jun 2013Pairs of gene-regulating proteins work together to identify their proper binding sites within the genome