Drug discovery

A new chemical testing platform harnesses colour- and light-producing genes from wildlife to speed the search for promising RNA-based therapeutics.

A new molecular dynamics study reveals how some stapled peptides shapeshift to slip through cellular barriers and target key disease-related proteins within cells.

High iron levels, often linked to red meat consumption, can fuel cancer growth by reactivating proteins that allow cancer cells to divide endlessly.

Innovative designer molecules called stapled peptides effectively target and block cancer processes, promising a new therapeutic approach.

Molecular simulations uncover a new druggable pocket in SARS-CoV-2’s spike protein which could hold the key to blocking COVID-19 infections.

A newly-designed antimicrobial polymer offers a 2-in-1 solution to combat multidrug-resistant bacteria.

The discovery of a new, highly conserved druggable site on the HIV reverse transcriptase could turn the tide in the wake of growing drug resistance.

When combined with low doses of antibiotics, this biodegradable polymer can reduce or even reverse antimicrobial resistance.

A new method of identifying drug targets in the malaria parasite P. falciparum could find broad applications in other fields of biology.

Could there be a drug that can both treat and protect against COVID-19? The answer may be found in antibody drugs, a promising therapeutic modality against the coronavirus.

Uttam Surana shares how SiNOPSEE Therapeutics, the biopharmaceutical startup he co-founded, is developing drugs to block angiogenesis in cancer and degenerative eye conditions.

Tipped off by artificial intelligence, a research team is testing whether a rheumatoid arthritis drug could be repurposed as a COVID-19 treatment.