Embryonic stem cells

The key to efficient production of heart muscle from pluripotent stem cells lies in optimizing the density and replicative state of the starting material

Two proteins maintain embryonic stem cell pluripotency
through different means

The rate of protein production in differentiating stem cells is controlled by more complex factors than previously thought

Researchers show how human embryonic stem cells maintain the potential to differentiate into almost any cell type, but enter a death pathway if damaged

A new strategy minimizes the cellular contaminants that usually plague the differentiation of pluripotent stem cells

Cultured human embryonic stem cells given the ‘3iL’ treatment more closely resemble natural stem cells from the developing embryo

A protein called SON ensures proper splicing of proteins to keep embryonic stem cells in a state of self-renewal

A regulatory protein called HEXIM1 induces human pluripotent stem cells to adopt a more specialized cell fate

Proper embryonic development depends on a signaling pathway that helps to preserve stem cell ‘immaturity’

A location map for a signaling protein identifies key molecular targets in human embryonic stem cells