Epigenetics

Researchers reveal how disrupting a key genetic control mechanism can significantly hinder the progression and spread of an aggressive and difficult-to-treat form of breast cancer.

A*STAR researchers identified the mechanism behind how a common gene mutation in kidney cancer impacts chromatin remodelling and drives tumour development, opening up new possibilities for therapeutic interventions.

Researchers develop a protocol to boost the effectiveness of and reduce the risk of potential side effects for T cell cancer therapies.

Cancer genetics experts say new technologies and more comprehensive data collection are required to deepen our understanding of tumour lifecycles.

Researchers have pieced together a series of molecular events that trigger the progression of chronic myeloid leukemia to its acute phase—the ‘blast crisis.’

Disruption of the methionine cycle in tumor-initiating cells disarms their tumorigenic capabilities, researchers say.

State-of-the-art single-cell RNA sequencing technologies shed light on the mechanisms through which cancer cells become resistant to tumor-treating drugs

A dual-function protein switch can be tweaked to improve the effectiveness of cellular reprogramming

Molecular dissection of bile duct cancer reveals subtypes with different origins and varying potential treatments

Researchers
discover a master regulator of nose development

First roadmap of stomach cancer super-enhancers paves the way for new treatments.

A sensitive DNA profiling technique could improve scientists’ approach to fighting cancer drug resistance