Epigenetics
Tenacious T cells triumph over tumours
18 Aug 2023Researchers develop a protocol to boost the effectiveness of and reduce the risk of potential side effects for T cell cancer therapies.
A wide-angle view of cancer evolution
29 Jul 2022Cancer genetics experts say new technologies and more comprehensive data collection are required to deepen our understanding of tumour lifecycles.
Reversing a cancer crisis
13 Nov 2020Researchers have pieced together a series of molecular events that trigger the progression of chronic myeloid leukemia to its acute phase—the ‘blast crisis.’
Crippling cancer cell growth
29 Jul 2019Disruption of the methionine cycle in tumor-initiating cells disarms their tumorigenic capabilities, researchers say.
Poised for survival
16 Apr 2019State-of-the-art single-cell RNA sequencing technologies shed light on the mechanisms through which cancer cells become resistant to tumor-treating drugs
How a cell’s fate is controlled
15 Nov 2018A dual-function protein switch can be tweaked to improve the effectiveness of cellular reprogramming
Classify and conquer
12 Dec 2017Molecular dissection of bile duct cancer reveals subtypes with different origins and varying potential treatments
Mutation found in patients without a nose
14 Sep 2017Researchers
discover a master regulator of nose development
Powerful switches discovered
25 Jul 2017First roadmap of stomach cancer super-enhancers paves the way for new treatments.
Revealing the blueprints
29 Nov 2016A sensitive DNA profiling technique could improve scientists’ approach to fighting cancer drug resistance
Reading the genome through a sharper lens
19 Jul 2016A neglected histone modification has unexpected implications for gene activity
Regulatory regions revealed in one shot
5 Jan 2016Disease-causing regions of the genome that affect gene expression levels are mapped with a new method