Genomics

Genomic differences between individuals can change the physical organization of RNA transcripts, affecting their expression

A new technique allows biologists to profile patterns of gene regulation in clinical specimens and other rare cell populations

A*STAR’s Single-Cell Omics Centre, the first research center in Asia exclusively dedicated to accelerating the understanding of how individual cells work, officially opened in April 2013

A new computer program readily identifies rare mutations harbored within diverse populations of cancer cells and microorganisms

The sweet orange’s parents and mechanism for producing vitamin C are revealed in its draft genome sequence

In a world’s first, Singaporean scientists have discovered the genes responsible for cornea blindness, providing valuable information for treatment and prevention of degenerative eye diseases

Gene regulatory proteins may be more flexible in their DNA binding preferences than previously expected

New study provides mechanistic insights into how gene transcription is regulated in mammalian cells

Variations in immune genes associated with increased susceptibility to common kidney disease

Genome-wide association studies reveal risk factors that increase the susceptibility of children to certain diseases

Embryonic stem cell researchers collaborate to uncover genomic changes that might favor cancerous growth

A new computer program provides a more accurate way of assembling DNA sequences from fragmented data