Genomics

A genome-wide association study has identified genetic variations associated with the debilitating disease ankylosing spondylitis

DNA sequencing reveals how breast cancer cells rearrange their genome to create fusion genes for driving tumor development

A high-throughput sequencing strategy allows scientists to follow cancer’s trail of genomic destruction

Variations in three genes can affect the size of the optic disc, a structure in the eye that is larger in individuals with visual dysfunction

A genome-wide RNA interference screen identifies genes that govern the unique properties of human embryonic stem cells

A genome-wide association study identifies genetic factors that increase the risk of meningococcal disease

A large-scale genomic analysis yields insights into a cancer that disproportionately affects individuals from southern China

Cancer geneticists in Singapore seek clinical relevance in large-scale cancer genomics studies

Mammalian genomes display large differences where the regulatory proteins of their embryonic stem cells bind

Genomic technologies developed by A*STAR’s Singapore Immunology Network (SIgN) form the basis for a new vaccine development platform that could pave the way for cost-effective personalized therapy

Elephant sharks display the potential for color vision despite mainly residing in deep waters

Chromosomal looping enables genome-wide ‘remote control’ of transcription, and may help coordinate activity from multiple genes