A new analytical platform reveals signature changes in immune cells of the brain during aging and neurodegenerative conditions such as Alzheimer’s disease.
The first open-access database of mononuclear phagocytes, created by A*STAR researchers, provides insight into the biology of these immune cells and their roles in fighting disease.
New research techniques are enabling scientists like SIgN’s Florent Ginhoux to unravel the complexities of the immune system like never before.
Being able to distinguish between different types of macrophages in the brain could shed light on inflammatory diseases such as Alzheimer’s.
The developmental origins of human macrophages suggest that scientists may need to rethink the way they study these important immune cells.
effect of gut bacteria on specific immune cells is behind persistent liver
inflammation in chronic viral hepatitis
Immune cells localized near pancreatic cancer cells
have an altered metabolism and could be involved in promoting the spread of cancer
to other organs
Proof that CD14+ immune cells in the skin are derived from monocytes in the blood helps understand their function in regulating immunity
Advances in fluorescent probe technology could allow real-time visualization of cancer progression during surgery
Identification of a previously unknown interaction between immune-system cells points the way to novel cancer treatments