By enhancing stem cell proliferation, this newly developed heparan sulphate glycosaminoglycan bio-additive lowers the barriers to regenerative medicine.
Modifying how embryonic stem cells use sugar can switch them into a totipotent state, A*STAR researchers say.
From replacing the insulin producing cells of the body, to serving as genetic and drug screening platforms, stem cells could change the landscape of available treatments for diabetes.
If cell-based therapies are to make it to the clinic, methods to grow stem cells in vast quantities will need to be developed. Here’s how A*STAR scientists are tackling the challenge of manufacturing stem cells at scale.
By triggering the Wnt signaling pathway, A*STAR scientists were able to reactivate proliferation in mature human heart muscle cells.
A carefully defined balance of biomolecular signals stimulates healing by setting skin cells into motion
Stem cells that can produce both major lung tissue types have been isolated and can now repair the damaged lungs of mice
A new antibody could hold the secret to making stem cell therapy safer
Understanding how a protein influences early heart development could help scientists develop better regenerative therapies.
Insights into how external mechanical
forces affect stem cell behavior could advance regenerative medicine efforts
Fluorescent tagging enables scientists to monitor neural stem cells that might help repair neurological damage