Regenerative medicine

Researchers use single-cell sequencing for a new look at how stem cell-derived retinal cells fare after transplants for degenerative eye disorders.

A*STAR researchers challenge existing theories around intestinal stem cell biology using a newly developed animal model of intestinal regeneration.

A breakthrough stem cell transplant technology uses donated cadaver eyes to restore vision in patients with retinal degeneration.

A*STAR researchers have created the first machine learning model for predicting clinical outcomes of stem cell therapies in patients with cartilage disorders.

Scientists identify a key molecular marker of muscle stem cells, providing novel insights into the mechanisms around muscle regeneration.

When placed in the proper environment, even stem cells from unlikely sources like the bladder or prostate can form skin components like hair follicles and sebaceous glands.

Single-cell techniques have helped to identify a key molecular switch controlling how adult cells can be turned back to a stem cell-like state.

A novel genomic biomarker may help to meet the demand for donor mesenchymal stem cells in regenerative medicine.

By enhancing stem cell proliferation, this newly developed bio-additive lowers the barriers to regenerative medicine.

Modifying how embryonic stem cells use sugar can switch them into a totipotent state, A*STAR researchers say.

From replacing the insulin producing cells of the body, to serving as genetic and drug screening platforms, stem cells could change the landscape of available treatments for diabetes.

If cell-based therapies are to make it to the clinic, methods to grow stem cells in vast quantities will need to be developed. Here’s how A*STAR scientists are tackling the challenge of manufacturing stem cells at scale.