Researcher

Roland Huber is a Principal Investigator for Structure and Function of RNA and program lead for AI and Emerging Technologies at the A*STAR Bioinformatics Institute (A*STAR BII). Huber studied computational biology at the University of Innsbruck, Austria, and Yale University, US. His research focuses on the interplay of structure and function of RNA in diseases, nucleic acid therapeutics development and RNA manufacturing.

Using statistical modelling, machine learning, multi-omics data and molecular simulations, Huber’s team investigates functional mechanisms of folded RNA and RNA-protein complexes, including how to use RNA as a drug and RNA as a drug target. Therapeutic areas of interest comprise tropical and emerging infectious diseases and cancer. Huber’s team also works on biotechnological problems of RNA manufacturing and delivery.