Yue Zhang is a Scientist at the A*STAR Bioprocessing Technology Institute. Her research focuses on developing nucleic acid therapeutic delivery technologies for disease treatment. She has developed delivery strategies for gene-editing and gene-activation tools, including CRISPR/Cas9 and CRISPRa, using mRNA- and plasmid DNA-based approaches to reprogram immune cells or repurpose tumour cells for the treatment of transplant rejection and cancer. Her work also explores engineering and in vivo delivery of multimeric protein therapeutics and membrane proteins for cancer therapy. Her current research focuses on developing safer and more effective LNP-enabled mRNA vaccines and therapeutics.
