Antibodies
Getting the SARS-CoV-2 antibody response straight
29 Jun 2020Two linear peptides identified by A*STAR researchers on the SARS-CoV-2 spike protein may improve the specificity of serological assays and show potential as vaccine candidates.
Sweet serendipity unveils anticancer strategy
29 Nov 2019A better understanding of the way sugar units are attached to the surface proteins of cancer cells may help to improve targeted cancer treatments, A*STAR scientists say.
Engineering a safer antibody drug
1 May 2018By taking advantage of the body’s
natural diversity, antibody drugs can be made less toxic by having a more localized
effect
Shedding ‘light’ on antibody design
28 Nov 2017The
light chain subunits of therapeutic antibodies impact drug performance and yield
A dengue treatment that is one ‘four’ all
19 Sep 2017An antibody that targets all four strains of the virus
renews hope for effectively treating and preventing dengue
Sidling up to natural killers
22 Mar 2016A technique to generate antibodies that can help strengthen natural immune responses to cancer and leukemia has been developed
Resource for drug developers helps pick linkers
22 Mar 2016SynLinker offers a better way to design fusion protein drugs
Fine-tuning immune cell function
10 Feb 2016The function of mature B cells is regulated by a small genomic cluster called mir-17-92
A sticky situation
19 Jan 2016Examining the intermediate stages of antibody purification provides
insight into the manufacture of safer biopharmaceuticals at lower cost
Telling mosquito-borne viruses apart
20 Oct 2015A novel diagnostic test for Chikungunya
virus also helps distinguish the illness from other mosquito-borne diseases
Pushing for greater purity
24 Sep 2015A standard purification process changes the structure of antibodies — and then changes them back
Tallying white blood cells on paper
14 Jul 2015A cost effective means for counting white blood cells promises to improve diagnosis in low-resource areas