A*STAR Bioinformatics Institute (A*STAR BII)
Stapling together cancer therapy
6 May 2014Computer simulations help design molecules with potential as a cancer therapy
Gaining the upper hand
21 Jan 2014Human–computer interactions could be improved by a new efficient and accurate hand-gesture-recognition model
All sorted on a single microchip
13 Aug 2013A microchip that can identify human pathogens in a single test could revolutionize the diagnosis of infections
Targeting tumors with ‘stapled’ peptides
16 Jul 2013Designer peptides containing chemically stabilized helices emerge as a potent way to activate anti-tumor proteins inside cells
‘See-saw’ switch sends cells on the march
21 May 2013An unusual switching mechanism that determines a single gene’s RNA output directly controls wound healing
A faster way to untangle intermolecular interactions
29 Jan 2013More effective medicines could result from a method that improves simulations of the binding interactions between drugs and their targets
The twists and turns of tumor treatment
22 Nov 2011A melanoma drug is linked to long-term changes in the tumor environment in a subset of tumors that respond effectively to the drug
Cooperative partners
8 Nov 2011Structural analysis indicates how two different antibodies to a cancer-causing protein could work together to block its function
Out of the loop
28 Sep 2010Molecular dynamics simulations show why scientists have failed to generate an active form of the protein kinase PAK1
A protein witnessing 30 years of evolution in cancer research
22 Dec 2009Cancer-suppressor protein p53 has undergone dramatic shifts in understanding over the past 30 years, but now scientists are entering a new era in the development of novel p53-based therapies.
