A*STAR Bioprocessing Technology Institute (A*STAR BTI)
Enhancing the immune response to fungal infections
20 Dec 2019A*STAR scientists have found a way to boost the activity of neutrophils, a subset of immune cells, against disease-causing fungi.
Scaling up for success
29 Nov 2019If cell-based therapies are to make it to the clinic, methods to grow stem cells in vast quantities will need to be developed. Here’s how A*STAR scientists are tackling the challenge of manufacturing stem cells at scale.
Crippling cancer cell growth
29 Jul 2019Disruption of the methionine cycle in tumor-initiating cells disarms their tumorigenic capabilities, researchers say.
How cancer cells tip the Bim balance in their favor
24 May 2019Cancer cells evade Taxol-induced cell death by downregulating the expression of a protein known as BimEL.
How bacteria influence host immunity
24 May 2019When parts of a bacteria’s cell wall enter into circulation, its host experiences more severe autoimmune reactions.
New stem cell antibody targets cancer
14 Jan 2019An antibody that targets a protein on the surface of stem cells also targets the same protein on some cancer cells
Making heart tissue ‘beat’
14 Jan 2019The key to efficient production of heart muscle from pluripotent stem cells lies in optimizing the density and replicative state of the starting material
Uncapping a new therapy
19 Dec 2018A deeper understanding of chromosome capping could improve therapies for both cancer and aging
Unlocking new antibiotics
19 Dec 2018Leveraging the power of CRISPR-Cas9 to awaken antibiotics from their silent gene clusters
Blood factories closer to reality
29 Nov 2018With
an eye to transfusion for patients, researchers are getting close to growing huge
numbers of red blood cells in industrial-grade vats
The fats that identify disease
7 Sep 2017Excess fluid
surrounding the lungs in some lung cancer patients has a unique lipid
profile, which could help diagnose and treat the disease
A signal of safe therapy
14 Jun 2017A new antibody could hold the secret to making stem cell therapy safer