Bioprocessing Technology Institute (BTI)
A protein known to switch on DNA repair genes also ‘pauses’ the cell cycle in response to DNA damage, A*STAR researchers find.
Modifying how embryonic stem cells use sugar can switch them into a totipotent state, A*STAR researchers say.
A*STAR scientists have found a way to boost the activity of neutrophils, a subset of immune cells, against disease-causing fungi.
If cell-based therapies are to make it to the clinic, methods to grow stem cells in vast quantities will need to be developed. Here’s how A*STAR scientists are tackling the challenge of manufacturing stem cells at scale.
Disruption of the methionine cycle in tumor-initiating cells disarms their tumorigenic capabilities, researchers say.
Cancer cells evade Taxol-induced cell death by downregulating the expression of a protein known as BimEL.
When parts of a bacteria’s cell wall enter into circulation, its host experiences more severe autoimmune reactions.
An antibody that targets a protein on the surface of stem cells also targets the same protein on some cancer cells
The key to efficient production of heart muscle from pluripotent stem cells lies in optimizing the density and replicative state of the starting material
A deeper understanding of chromosome capping could improve therapies for both cancer and aging
Leveraging the power of CRISPR-Cas9 to awaken antibiotics from their silent gene clusters