A*STAR Bioprocessing Technology Institute (A*STAR BTI)
A safe way to manipulate immune cells
7 Oct 2014An optimized technique allows B cells to be transfected with extraneous DNA without the use of viruses
Small particles, big productivity
12 Aug 2014Magnetic nanoparticles break the capacity barrier for antibody purification
Putting production in proportion
15 Jul 2014A library of sequences that modify relative gene expression enables tighter control over protein production
Sugarcoating a protein drug
3 Jun 2014Mammalian cells have been engineered to produce longer-lived versions of the therapeutic protein erythropoietin
Focusing on the sweet spot
11 Mar 2014A novel targeted mass spectrometry technique uncovers an elusive sugar modification in stem cells
A HEX that coaxes differentiation
17 Dec 2013A regulatory protein called HEXIM1 induces human pluripotent stem cells to adopt a more specialized cell fate
A biomarker for myeloma
2 Jul 2013A protein called FAIM could help doctors to parse which cancer patients will respond to multiple myeloma therapy
Convection trumps diffusion
21 May 2013Breakthrough technology quickly separates large proteins and viruses from their surroundings, which improves purification of vaccines and protein therapuetics
Accelerating cellular assembly lines
1 Jan 2013Insights into cellular productivity could boost generation of proteins with valuable research and medical applications
Laboratory bioreactor boosts yields
4 Dec 2012Inducing stem cells to become different cell types efficiently, and on a large scale, is now possible using a three-dimensional platform
Making sense of contradictions
20 Nov 2012Researchers from A*STAR explain how defects in a signaling protein sabotage the immune system in multiple, seemingly contradictory ways
A key checkpoint against infection
14 Aug 2012A single enzyme plays a critical role in helping the body effectively fight viral infection