Cancer

Exploiting a mutation in a key tumor-fighting protein may provide a new opportunity to treat aggressive lung cancers.

A protein known to switch on DNA repair genes also ‘pauses’ the cell cycle in response to DNA damage, A*STAR researchers find.

Researchers have pieced together a series of molecular events that trigger the progression of chronic myeloid leukemia to its acute phase—the ‘blast crisis.’

A study implicates novel genetic risk factors in a rare and aggressive lymphoma affecting Asian populations.

A novel targeting strategy may make pave the way for effective cancer immunotherapy against previously ‘undruggable’ targets.

Cancer cells evade Taxol-induced cell death by downregulating the expression of a protein known as BimEL.

State-of-the-art single-cell RNA sequencing technologies shed light on the mechanisms through which cancer cells become resistant to tumor-treating drugs

Drug screen reveals safe, potent, broad-spectrum anticancer compound

A new imaging method could reduce the number of repeat operations for breast cancer

An antibody that targets a protein on the surface of stem cells also targets the same protein on some cancer cells

A deeper understanding of chromosome capping could improve therapies for both cancer and aging

Mouse studies have revealed more about the mechanisms
behind cancer drugs in trials