Drug resistance

The ability of cells to adapt to the loss of some genes previously thought vital for survival challenges the concept of gene essentiality

Polymers that can be fine-tuned for optimal effect could help fight multidrug-resistant infections

Cationic small molecules hold great potential for preventing and treating fungal infections

A hydrogel with potent antibacterial activity promises to protect hospital patients from difficult-to-treat infections

Our antibiotic armory is set to benefit from the development of short-chain synthetic polymers with potent efficacy against multidrug-resistant microbes

On the back of growing drug resistance, researchers at the A*STAR Institute of Molecular and Cell Biology are exploring new targets to develop effective antibacterial compounds

The antifolate drug methotrexate is highly potent against the malaria parasite Plasmodium vivax

A strain of H1N1 influenza virus that rapidly develops resistance to the antiviral drug oseltamivir has emerged

An investigation into how some cancers evade treatment reveals a novel pathway regulating tumor growth