Epigenetics

A neglected histone modification has unexpected implications for gene activity

Disease-causing regions of the genome that affect gene expression levels are mapped with a new method

High levels
of DNA methylation at a particular genetic location are linked to greater birth
weight and higher adiposity

New roles revealed for immune-regulatory protein may have significant clinical implications

A detailed study of infants and mothers before and after birth provides valuable insights

A specific ratio of DNA packaging proteins ensures normal gene expression during early embryonic development

A new technique allows biologists to profile patterns of gene regulation in clinical specimens and other rare cell populations