Genes

Increasing the efficacy and minimizing unwanted side effects of cancer gene therapy has been made possible using a new approach

Single-cell gene expression profiling reveals specific genetic programs underlying cell differentiation in pre-implantation mouse embryos

Analysis of the genome of a primitive seafloor dweller shows that a well-known system for controlling DNA damage is highly conserved evolutionarily

A large-scale genomic study identifies genes associated with bowel disease and provides clues to their functions

A protective polymer shell enhances virus-mediated in vivo gene delivery

Stabilization of a tumor-inducing protein by the human papillomavirus protein E2 may be an early step in cervical tumor formation

A sophisticated algorithm combines expression data with information about patient outcomes to reveal cancer genes

Elephant sharks display the potential for color vision despite mainly residing in deep waters

A small RNA molecule has a big influence on the activity of an important tumor suppressor

MicroRNA molecules represent an important regulatory roadblock preventing cancer cell proliferation

Cancer-suppressor protein p53 has undergone dramatic shifts in understanding over the past 30 years, but now scientists are entering a new era in the development of novel p53-based therapies.

Genetic evidence reveals that an enzyme that deactivates signaling pathways is associated with inflammation and cancer