Genes

A melanoma drug is linked to long-term changes in the tumor environment in a subset of tumors that respond effectively to the drug

Gene regulation may depend more on the synergy of multiple proteins rather than discrete contributions of individual factors

A protein secreted from breast cancer cells enhances the spread and survival of tumor cells

Generating microbes with useful properties is quicker and easier if multiple genes are modified at the same time

Self-healing skin cancer and Loeys–Dietz syndrome are caused by mutations in the same gene

The discovery of a rare genetic mutation sheds new light on bone and limb development

Efforts to understand a signaling factor’s contradictory behavior reveal a master switch for organ development

Genetic variations related to estrogen production have a cumulative effect on breast and endometrial cancer risk

HPV18 puts women at a higher risk of developing cervical cancer because the virus converts a repressor of the cell cycle into an activator

A highly truncated receptor protein variant retains the ability to modulate metabolic activity in mice

Discovery of the mechanism regulating the expression of an enzyme implicated in human cancer could open new avenues for treatment

Mysterious molecules called lncRNA direct the fate of stem cells in the early mouse embryo