A*STAR Genome Institute of Singapore (A*STAR GIS)

Targeting a key gene can help prevent the body’s immune fighters from wearing out when attacking tumour cells, offering a new treatment strategy against cancer.

A*STAR researchers discover how subtle changes to a packaging component of mRNA vaccines can boost their efficacy and safety.

Integrating molecular insights from several omics profiling approaches, A*STAR research initiatives are deepening our understanding of human physiology and unearthing new diagnostic and therapeutic opportunities.

From innovative medical devices to advanced manufacturing partnerships, the work of A*STAR recipients of the 2024 President’s Science and Technology Awards exemplify the importance of translating research into clinical and commercial outcomes.

Scientists identify a new, distinct group of the deadly yeast Candida auris, and urge the expansion of global surveillance efforts.

A large-scale gut microbiome study in elderly Singaporeans reveals new insights into the role of our resident microbes in healthy ageing.

A detailed map of genetic variations in a key drug-processing enzyme reveals new precision medicine insights for patients of Asian ancestry.

Fascinated by genome editing’s potential, A*STAR scholar Chen Gang Goh is advancing research on DNA repair pathways and their implications for gene therapy in cancer.

Cell and gene therapies are driving the next revolution in medicine, combining the best of biology with game-changing technologies from A*STAR researchers and partners.

A comprehensive study of liver tumours reveals that a small fraction of aggressive cells can have an outsized effect on patient outcomes.

High iron levels, often linked to red meat consumption, can fuel cancer growth by reactivating proteins that allow cancer cells to divide endlessly.

In recognition of their scientific contributions and impact both locally and globally, 14 leading researchers have been awarded the 2024 A*STAR Fellowship.