Human Health and Potential (HHP)

Understanding why COVID-19 tends to strike the old but spare the young could inform how to prioritize limited COVID-19 vaccines.

Single-cell techniques have helped to identify a key molecular switch controlling how adult cells can be turned back to a stem cell-like state.

A*STAR researchers identify a novel mechanism in which an inflammatory protein heals wounds in healthy individuals but has the opposite effect in diabetics.

Controlling the delicate balance between immune cells called granulocytes and monocytes could make the difference between a healthy immune response and life-threatening sepsis.

Four newly discovered SARS-CoV-2 peptides not only promise to make COVID-19 tests cheaper and more specific, but may also reveal disease severity.

In a classic case of double trouble, the binding of SARS-CoV-2’s spike protein to bacterial lipopolysaccharide supercharges inflammation in COVID-19 patients.

The detailed structure of a testosterone-regulating enzyme is helping researchers to design better drugs for diseases such as prostate cancer.

Researchers have identified a pain pathway that suppresses hunger, opening the door to understanding how pain quells other competing behaviors.

Asian oil blends rich in healthy fats and phytonutrients are as good as—or even better than—olive oil for the heart.

When combined with low doses of antibiotics, this biodegradable polymer can reduce or even reverse antimicrobial resistance.

Liver tumors gain immune tolerance by activating cellular mechanisms involved in fetal development.

For the first time, researchers have generated lab-grown livers that have functioning bile canaliculi, an important step towards modeling complex liver diseases.