Infection
The rediscovered origin of an immune cell subtype
29 Nov 2019By mapping the development trajectory of immune precursor cells, A*STAR scientists showed that plasmacytoid dendritic cells were incorrectly classified in the immune ‘family tree.’
Clotting agent fragments help reduce sepsis risk
19 Dec 2018Small fragments of the coagulating protein thrombin may reduce the likelihood of bacterial wound infection leading to sepsis
Getting a grip on hand, foot and mouth disease
19 Dec 2018Testing for human microRNA in saliva could help prevent outbreaks of hand, foot and mouth disease in children
Hepatitis B exploits the liver’s weaknesses
12 Feb 2018In revealing
the liver’s ‘weak spot’ for hepatitis B virus replication, A*STAR scientists
are paving the way for new drug development efforts
A dengue treatment that is one ‘four’ all
19 Sep 2017An antibody that targets all four strains of the virus
renews hope for effectively treating and preventing dengue
A cautionary tale for immunotherapy
9 Aug 2017A failed treatment for chikungunya highlights the need for extreme caution when manipulating the immune system
Molecular ‘movie’ reels viral envelope into shape
24 Jan 2017Computer simulations reveal every curve of the dengue capsule
Putting a block on inflammation
15 Dec 2015Limiting immune response can reduce joint injury caused by the mosquito-borne Chikungunya virus
Hosting unwelcome guests
17 Nov 2015A trawl through the human genome for factors in the replication of bronchitis virus in human lung cells reveals pathways that can be targeted for therapeutic development
For one and for all
5 Jun 2012The infection of one dengue virus subtype can lead to the production of antibodies that confer protection against other dengue virus subtypes
Patrolling skin for pathogens
17 Jan 2012The inner layer of skin contains a population of immune cells specialized for fighting infection
A new breath of life
17 Jan 2012The discovery of distal airway stem cells opens the door to new therapies for reversing pulmonary disease