Institute of Medical Biology (IMB)

A*STAR scientists have identified stem cells required for successful embryo implantation during pregnancy.

Bortezomib, a drug that inhibits the ‘waste disposal system’ in animal cells, could be used to suppress cell division in cancer.

Researchers at A*STAR have combined two superresolution microscopy techniques to observe structural protein dynamics inside cells.

A protein named GATA6 is key to the development of a normal pancreas in humans.

Researchers have obtained a high-resolution structure of the RIP2 protein complex and detailed its interactions with other immune proteins.

By turning a pathogenic yeast into an immunity-conferring symbiont, a team of A*STAR researchers is unraveling mysteries behind gut evolution and universal vaccines

The size and composition of protein-binding sugars in the extracellular matrix play a crucial role in bone repair

Thermal stress elicits genomic changes that can make cancer cells resistant to chemotherapy

A carefully defined balance of biomolecular signals stimulates healing by setting skin cells into motion

A deeper understanding of chromosome capping could improve therapies for both cancer and aging

Assay combines microfluidics and next-generation sequencing to reveal more mutations than existing targeted gene tests

A microfluidic organ-on-a-chip device combines skin culture and testing capabilities to offer a substitute to animal testing