Institute of Medical Biology (IMB)
Bringing the womb to birth
24 Jan 2020A*STAR scientists have identified stem cells required for successful embryo implantation during pregnancy.
A stabilizing strategy to keep cancer cells in check
29 Nov 2019Bortezomib, a drug that inhibits the ‘waste disposal system’ in animal cells, could be used to suppress cell division in cancer.
Advanced microscopy catches cells going out on a limb
23 Sep 2019Researchers at A*STAR have combined two superresolution microscopy techniques to observe structural protein dynamics inside cells.
Writing the roadmap for pancreas development
28 Jun 2019A protein named GATA6 is key to the development of a normal pancreas in humans.
A RIPple effect during infection
14 Jun 2019Researchers have obtained a high-resolution structure of the RIP2 protein complex and detailed its interactions with other immune proteins.
Against gut instinct
2 Apr 2019By turning a pathogenic yeast into an immunity-conferring symbiont, a team of A*STAR researchers is unraveling mysteries behind gut evolution and universal vaccines
Sweetening the deal on bone repair
17 Mar 2019The size and composition of protein-binding sugars in the extracellular matrix play a crucial role in bone repair
Drug resistance in the hot seat
21 Feb 2019Thermal stress elicits genomic changes that can make cancer cells resistant to chemotherapy
Releasing the brakes on wound repair
14 Jan 2019A carefully defined balance of biomolecular signals stimulates healing by setting skin cells into motion
Uncapping a new therapy
19 Dec 2018A deeper understanding of chromosome capping could improve therapies for both cancer and aging
DNA test reveals genetic risk factors for eczema
29 Aug 2018Assay combines microfluidics and next-generation sequencing to reveal more mutations than existing targeted gene tests
Reconstructing skin on a chip
15 Aug 2018A microfluidic organ-on-a-chip device combines skin culture and testing capabilities to offer a substitute to animal testing