Institute of Medical Biology (IMB)

The balance of renewal and differentiation of the skin’s stem cells is regulated by factors secreted by the cells themselves

Tiny vesicles secreted by mesenchymal stem cells can modulate the immune system and prevent the rejection of grafted tissue

Newly identified hormone ELABELA regulates the generation of the embryo’s endoderm and is required for the normal formation of the heart

Single-cell analysis shows how embryonic cells maintain proper patterns of gene regulation   

A specific ratio of DNA packaging proteins ensures normal gene expression during early embryonic development

A newly discovered early-warning system triggers cellular suicide when a critical RNA editing system breaks down

Proper embryonic development depends on a signaling pathway that helps to preserve stem cell ‘immaturity’

Two proteins that control nuclear DNA distribution also regulate development by altering gene expression

Revelation of how photoreceptive cells in the eye distinguish between different light sources could pave the way for a novel class of optical devices

An unusual switching mechanism that determines a single gene’s RNA output directly controls wound healing

Proper cell–cell interactions are required for the cells of early embryos to develop normally

A repressor protein that blocks differentiation-specific genes helps maintain stem cells’ ability to develop into any cell type