A*STAR Institute of Molecular and Cell Biology (A*STAR IMCB)

A comprehensive genomic map reveals how certain genes regulate key cells in blood sugar control, offering new insights for future diabetes treatments.

Researchers developed a new method to improve the effectiveness of islet cell transplants, which may offer better treatment options for people with diabetes.

Innovative designer molecules called stapled peptides effectively target and block cancer processes, promising a new therapeutic approach.

A new optical scanner reduces costs and expands medical imaging applications, enabling doctors to better view and diagnose internal body structures.

Enzymes from soil bacteria can effectively break down some of the toughest plastic pollutants, offering a promising approach to tackling plastic waste.

Using artificial intelligence techniques, Mai Chan Lau maps the spatial relationships between tumour cells and immune cells to understand their effect on clinical outcomes.

As the immune system ages, our susceptibility to conditions such as cancer increases, prompting researchers to develop advanced experimental models to study these pathways.

Neutrophils, typically our immune defenders, can paradoxically promote cancer progression when altered in tumours.

Researchers find that targeting nerve growth factor in melanomas transforms resistant ‘cold’ tumours into treatable ‘hot’ ones, adding new therapeutic options for challenging skin cancers.

To unlock new insights into human neural development and disease, biomaterials specialist Wai Hon Chooi aims to develop three-dimensional human tissue models that accurately replicate their natural counterparts.

Drawing together artificial intelligence, robotics and medicine, Gaurav Manek is developing advanced microscopes that can help guide surgeons minimise tissue removal during operations, aiding the recovery process.

Through innovative technologies and deep biological insights, A*STAR research institutes and ecosystem partners aim to enhance the healthspan of Asia’s ageing populations.