Molecular biology

Mutant zebrafish provide a model for an emerging class of human diseases

Small alterations to a chromosomal protein have far-reaching effects on gene expression activity

Scientists are establishing the basic molecular network of a new player involved in protein secretion and clarifying its regulation in mammalian cells

Molecular dynamics simulations show why scientists have failed to generate an active form of the protein kinase PAK1

A recently identified protein–protein interaction with key roles in brain development and function provides insights into mental retardation

A protein primarily active in the nucleus also operates within the cytoplasm to orchestrate cell movement

Blood vessel development in the pancreas is regulated by the signaling molecule STAT3

A complex molecular interaction signals when to terminate protein synthesis and release the product