RNA therapeutics

A novel RNA-based molecular tool offers an innovative way to detect, amplify and respond to genetic signals within cells with unprecedented modularity.

Researchers identify a molecular driver of cell death in a rare neurodegenerative disease and show how targeted oligonucleotide therapies can combat the process.

Self-looping molecules could be the key to unlocking the potential of RNA-based vaccines and therapies.

A new ‘liquid lipid’ approach that penetrates the nose’s mucus barrier could lead to needle-free, nasal spray-based mRNA vaccines.

Tumor growth in a mouse model of lung cancer is
reduced using an RNA-based therapeutic that inhibits a metabolic pathway in tumor-initiating
cells